Disorganization of cell division of methicillin-resistant Staphylococcus aureus by methanolic extract from Phyllanthus columnaris stem bark

A. Siti Noor Adnalizawati, Nazlina Ibrahim, Wan Yaacob Wan Ahmad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The in vitro activity of methanolic extract from Phyllanthus columnaris stem bark was studied against Methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 and MRSA BM1 (clinical strain) using time-kill curves in conjunction with scanning and transmission electron microscopy. The extract showed more markedly bactericidal activity in MRSA BM1 clinical strain within less than 4 h by 6.25-12.5 mg/mL and within 6 h by 1.56 mg/mL. Scanning electron microscopy of MRSA BM1 revealed distortion of cell whilst transmission electron microscopy revealed disruption in cell wall division.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages222-226
Number of pages5
Volume1571
DOIs
Publication statusPublished - 2013
Event2013 UKM Faculty of Science and Technology Post-Graduate Colloquium - Selangor
Duration: 3 Jul 20134 Jul 2013

Other

Other2013 UKM Faculty of Science and Technology Post-Graduate Colloquium
CitySelangor
Period3/7/134/7/13

Fingerprint

cell division
staphylococcus
stems
transmission electron microscopy
scanning electron microscopy
division
curves
cells

Keywords

  • CEll wall
  • Scanning electron microscopy
  • Transmission electron microscopy

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Disorganization of cell division of methicillin-resistant Staphylococcus aureus by methanolic extract from Phyllanthus columnaris stem bark. / Siti Noor Adnalizawati, A.; Ibrahim, Nazlina; Wan Ahmad, Wan Yaacob.

AIP Conference Proceedings. Vol. 1571 2013. p. 222-226.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Siti Noor Adnalizawati, A, Ibrahim, N & Wan Ahmad, WY 2013, Disorganization of cell division of methicillin-resistant Staphylococcus aureus by methanolic extract from Phyllanthus columnaris stem bark. in AIP Conference Proceedings. vol. 1571, pp. 222-226, 2013 UKM Faculty of Science and Technology Post-Graduate Colloquium, Selangor, 3/7/13. https://doi.org/10.1063/1.4858658
Siti Noor Adnalizawati, A. ; Ibrahim, Nazlina ; Wan Ahmad, Wan Yaacob. / Disorganization of cell division of methicillin-resistant Staphylococcus aureus by methanolic extract from Phyllanthus columnaris stem bark. AIP Conference Proceedings. Vol. 1571 2013. pp. 222-226
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