Discrepancy between the quantitative ultrasound value of malaysian men and the manufacturer's reference and the impact on classification of bone health status

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Abstract

The local normative value in quantitative ultrasound (QUS) equipment needs to be established for wider application and accurate classification of patients into respective fracture risk groups. The present study aimed to establish the calcaneal speed of sound (SOS) value for Chinese and Malay men in Malaysia and determine the difference between calcaneal SOS of the local population and the reference values provided by the manufacturer for each age group. This study will also determine the effect of using the manufacturer's young adult (20-29. yr) reference or the local young adult reference to classify the subjects into the respective risk groups. Eight hundred forty Malay and Chinese men residing in central peninsular Malaysia were recruited and their calcaneal QUS value was determined using the CM-200 machine (Furuno Electric, Nishinomiya City, Japan). The results showed that the differences in SOS values between Chinese and Malay men were not significant across all the age groups studied (p> 0.05). The age-dependent reduction of SOS value assumed a biphasic form, which was evident at 30-39. yr and older than 60. yr. The calcaneal SOS of the subject under study was significantly higher as compared with the manufacturer's reference (based on Japanese population) in all groups aged 40. yr and older (p< 0.05). A significant proportion of the subjects in the osteoporosis group was misclassified using the manufacturer's young adult reference as compared with using the local young adult reference (p<0.05). In conclusion, the overall normative value of SOS obtained was suitable for Chinese and Malay men in Malaysia, and a local reference value should be applied to avoid misclassification of subjects into the respective risk groups.

Original languageEnglish
Pages (from-to)189-195
Number of pages7
JournalJournal of Clinical Densitometry
Volume16
Issue number2
DOIs
Publication statusPublished - Apr 2013

Fingerprint

Health Status
Bone and Bones
Young Adult
Malaysia
Reference Values
Age Groups
Population
Osteoporosis
Japan
Equipment and Supplies

Keywords

  • Malaysian
  • Male
  • Normative value
  • Quantitative ultrasound
  • Speed of sounds

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Orthopedics and Sports Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

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title = "Discrepancy between the quantitative ultrasound value of malaysian men and the manufacturer's reference and the impact on classification of bone health status",
abstract = "The local normative value in quantitative ultrasound (QUS) equipment needs to be established for wider application and accurate classification of patients into respective fracture risk groups. The present study aimed to establish the calcaneal speed of sound (SOS) value for Chinese and Malay men in Malaysia and determine the difference between calcaneal SOS of the local population and the reference values provided by the manufacturer for each age group. This study will also determine the effect of using the manufacturer's young adult (20-29. yr) reference or the local young adult reference to classify the subjects into the respective risk groups. Eight hundred forty Malay and Chinese men residing in central peninsular Malaysia were recruited and their calcaneal QUS value was determined using the CM-200 machine (Furuno Electric, Nishinomiya City, Japan). The results showed that the differences in SOS values between Chinese and Malay men were not significant across all the age groups studied (p> 0.05). The age-dependent reduction of SOS value assumed a biphasic form, which was evident at 30-39. yr and older than 60. yr. The calcaneal SOS of the subject under study was significantly higher as compared with the manufacturer's reference (based on Japanese population) in all groups aged 40. yr and older (p< 0.05). A significant proportion of the subjects in the osteoporosis group was misclassified using the manufacturer's young adult reference as compared with using the local young adult reference (p<0.05). In conclusion, the overall normative value of SOS obtained was suitable for Chinese and Malay men in Malaysia, and a local reference value should be applied to avoid misclassification of subjects into the respective risk groups.",
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author = "{Kok Yong}, Chin and Soelaiman, {Ima Nirwana} and {Naina Mohamed}, Isa and Norazlina Mohamed and Shuid, {Ahmad Nazrun} and Norliza Muhammad and {Wan Ngah}, {Wan Zurinah}",
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T1 - Discrepancy between the quantitative ultrasound value of malaysian men and the manufacturer's reference and the impact on classification of bone health status

AU - Kok Yong, Chin

AU - Soelaiman, Ima Nirwana

AU - Naina Mohamed, Isa

AU - Mohamed, Norazlina

AU - Shuid, Ahmad Nazrun

AU - Muhammad, Norliza

AU - Wan Ngah, Wan Zurinah

PY - 2013/4

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N2 - The local normative value in quantitative ultrasound (QUS) equipment needs to be established for wider application and accurate classification of patients into respective fracture risk groups. The present study aimed to establish the calcaneal speed of sound (SOS) value for Chinese and Malay men in Malaysia and determine the difference between calcaneal SOS of the local population and the reference values provided by the manufacturer for each age group. This study will also determine the effect of using the manufacturer's young adult (20-29. yr) reference or the local young adult reference to classify the subjects into the respective risk groups. Eight hundred forty Malay and Chinese men residing in central peninsular Malaysia were recruited and their calcaneal QUS value was determined using the CM-200 machine (Furuno Electric, Nishinomiya City, Japan). The results showed that the differences in SOS values between Chinese and Malay men were not significant across all the age groups studied (p> 0.05). The age-dependent reduction of SOS value assumed a biphasic form, which was evident at 30-39. yr and older than 60. yr. The calcaneal SOS of the subject under study was significantly higher as compared with the manufacturer's reference (based on Japanese population) in all groups aged 40. yr and older (p< 0.05). A significant proportion of the subjects in the osteoporosis group was misclassified using the manufacturer's young adult reference as compared with using the local young adult reference (p<0.05). In conclusion, the overall normative value of SOS obtained was suitable for Chinese and Malay men in Malaysia, and a local reference value should be applied to avoid misclassification of subjects into the respective risk groups.

AB - The local normative value in quantitative ultrasound (QUS) equipment needs to be established for wider application and accurate classification of patients into respective fracture risk groups. The present study aimed to establish the calcaneal speed of sound (SOS) value for Chinese and Malay men in Malaysia and determine the difference between calcaneal SOS of the local population and the reference values provided by the manufacturer for each age group. This study will also determine the effect of using the manufacturer's young adult (20-29. yr) reference or the local young adult reference to classify the subjects into the respective risk groups. Eight hundred forty Malay and Chinese men residing in central peninsular Malaysia were recruited and their calcaneal QUS value was determined using the CM-200 machine (Furuno Electric, Nishinomiya City, Japan). The results showed that the differences in SOS values between Chinese and Malay men were not significant across all the age groups studied (p> 0.05). The age-dependent reduction of SOS value assumed a biphasic form, which was evident at 30-39. yr and older than 60. yr. The calcaneal SOS of the subject under study was significantly higher as compared with the manufacturer's reference (based on Japanese population) in all groups aged 40. yr and older (p< 0.05). A significant proportion of the subjects in the osteoporosis group was misclassified using the manufacturer's young adult reference as compared with using the local young adult reference (p<0.05). In conclusion, the overall normative value of SOS obtained was suitable for Chinese and Malay men in Malaysia, and a local reference value should be applied to avoid misclassification of subjects into the respective risk groups.

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