Dihydroflavonol and flavonol derivatives from Macaranga recurvata

Mulyadi Tanjung, Euis H. Hakim, Elfahmi, Jalifah Latip, Yana M. Syah

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Two new dihydroflavonol derivatives, macarecurvatins A and B, have been isolated from the leaves of Macaranga recurvata (Euphorbiaceaae), along with the known compounds diisoprenylaromadendrin, glyasperin A and broussoflavonol F. The structures of the new compounds were determined on the basis of spectroscopic evidence. Upon cytotoxic evaluation against P-388 cells, macarecurvatin B showed strong activity with an IC50 of 0.83 μM.

Original languageEnglish
Pages (from-to)1309-1310
Number of pages2
JournalNatural Product Communications
Volume7
Issue number10
Publication statusPublished - 2012

Fingerprint

Macaranga
Euphorbiaceae
flavonols
B-lymphocytes
inhibitory concentration 50
Inhibitory Concentration 50
leaves
3-hydroxyflavone
macarecurvatin B
macarecurvatin A

Keywords

  • Dihydroflavonol
  • Euphorbiaceae
  • Flavanol
  • Macaranga recurvata
  • Macarecurvatins A and B
  • P-388 cells

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Complementary and alternative medicine
  • Plant Science

Cite this

Tanjung, M., Hakim, E. H., Elfahmi, Latip, J., & Syah, Y. M. (2012). Dihydroflavonol and flavonol derivatives from Macaranga recurvata. Natural Product Communications, 7(10), 1309-1310.

Dihydroflavonol and flavonol derivatives from Macaranga recurvata. / Tanjung, Mulyadi; Hakim, Euis H.; Elfahmi, ; Latip, Jalifah; Syah, Yana M.

In: Natural Product Communications, Vol. 7, No. 10, 2012, p. 1309-1310.

Research output: Contribution to journalArticle

Tanjung, M, Hakim, EH, Elfahmi, , Latip, J & Syah, YM 2012, 'Dihydroflavonol and flavonol derivatives from Macaranga recurvata', Natural Product Communications, vol. 7, no. 10, pp. 1309-1310.
Tanjung, Mulyadi ; Hakim, Euis H. ; Elfahmi, ; Latip, Jalifah ; Syah, Yana M. / Dihydroflavonol and flavonol derivatives from Macaranga recurvata. In: Natural Product Communications. 2012 ; Vol. 7, No. 10. pp. 1309-1310.
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