Differential gene expression of human adipose-derived stem cells in osteogenic induction.

Adila A. Hamid, Ruszymah Idrus, B. S. Aminuddin, S. Sathappan, Chua Kien Hui

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Human adipose-derived stem cells (HADSC) have demonstrated the capacity of differentiating into bone depending on the specific induction stimuli and growth factors. However, investigation on stem cell characteristic after osteogenic differentiation is still lacking. The goal of this study was to investigate the differential expression of sternness and osteogenic genes in non-induced HADSC compared with HADSC after osteogenic induction using quantitative Real Time RT-PCR. Our results showed that OCT-4, REX-1, FZD9, OSC, RUNX, and ALP were up regulated after osteogenic induction. This may indicated that HADSCs after osteogenic induction still possessed some stemness properties.

Original languageEnglish
Pages (from-to)9-10
Number of pages2
JournalThe Medical journal of Malaysia
Volume63 Suppl A
Publication statusPublished - Jul 2008

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Stem Cells
Gene Expression
Real-Time Polymerase Chain Reaction
Intercellular Signaling Peptides and Proteins
Bone and Bones
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Differential gene expression of human adipose-derived stem cells in osteogenic induction. / A. Hamid, Adila; Idrus, Ruszymah; Aminuddin, B. S.; Sathappan, S.; Kien Hui, Chua.

In: The Medical journal of Malaysia, Vol. 63 Suppl A, 07.2008, p. 9-10.

Research output: Contribution to journalArticle

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