Dietary intake of aflatoxins in the adult Malaysian population - an assessment of risk

C. K. Chin, Aminah Abdullah, Y. Sugita-Konishi

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Exposure to aflatoxins in the adult Malaysian diet was estimated by analysing aflatoxins in 236 food composites prepared as "ready for consumption". Dietary exposure to aflatoxin B1 (AFB1) ranged from 24.3 to 34.00 ng/kg b.w./day (lower to upper bound), with peanuts being the main contributor. Estimated liver cancer risk from this exposure was 0.61-0.85 cancers/100,000 population/year, contributing 12.4%-17.3% of the liver cancer cases. Excluding AFB1 occurrence data higher than 15 μg/kg reduced exposure by 65%-91% to 2.27-11.99 ng/kg b.w./day, reducing the cancer risk to 0.06-0.30 cancers/100,000 population/year (contributing 1.2%-6.1% liver cancer cases). Reducing further the ML of AFB1 from 15 to 5 μg/kg yielded 3%-7% greater drop in the exposure to 0.47-10.26 ng/kg b.w./day with an estimated risk of 0.01-0.26 cancers/100,000 population/year (0.2%-5.1% liver cancer cases attributed to dietary AFB1). These findings indicate that current MLs are adequate in protecting Malaysians' health.

Original languageEnglish
Pages (from-to)286-294
Number of pages9
JournalFood Additives and Contaminants: Part B Surveillance
Volume5
Issue number4
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Aflatoxin B1
Aflatoxins
liver neoplasms
aflatoxin B1
Liver Neoplasms
aflatoxins
Liver
risk assessment
food intake
neoplasms
Population
Neoplasms
dietary exposure
Nutrition
peanuts
Health
Diet
Food
Composite materials
diet

Keywords

  • aflatoxin B1 (AFB1)
  • dietary exposure
  • liver cancer risk
  • total aflatoxins (AFT)

ASJC Scopus subject areas

  • Food Science
  • Public Health, Environmental and Occupational Health
  • Toxicology

Cite this

Dietary intake of aflatoxins in the adult Malaysian population - an assessment of risk. / Chin, C. K.; Abdullah, Aminah; Sugita-Konishi, Y.

In: Food Additives and Contaminants: Part B Surveillance, Vol. 5, No. 4, 12.2012, p. 286-294.

Research output: Contribution to journalArticle

@article{9ab719bd4ac64f10b625ff3693521fb1,
title = "Dietary intake of aflatoxins in the adult Malaysian population - an assessment of risk",
abstract = "Exposure to aflatoxins in the adult Malaysian diet was estimated by analysing aflatoxins in 236 food composites prepared as {"}ready for consumption{"}. Dietary exposure to aflatoxin B1 (AFB1) ranged from 24.3 to 34.00 ng/kg b.w./day (lower to upper bound), with peanuts being the main contributor. Estimated liver cancer risk from this exposure was 0.61-0.85 cancers/100,000 population/year, contributing 12.4{\%}-17.3{\%} of the liver cancer cases. Excluding AFB1 occurrence data higher than 15 μg/kg reduced exposure by 65{\%}-91{\%} to 2.27-11.99 ng/kg b.w./day, reducing the cancer risk to 0.06-0.30 cancers/100,000 population/year (contributing 1.2{\%}-6.1{\%} liver cancer cases). Reducing further the ML of AFB1 from 15 to 5 μg/kg yielded 3{\%}-7{\%} greater drop in the exposure to 0.47-10.26 ng/kg b.w./day with an estimated risk of 0.01-0.26 cancers/100,000 population/year (0.2{\%}-5.1{\%} liver cancer cases attributed to dietary AFB1). These findings indicate that current MLs are adequate in protecting Malaysians' health.",
keywords = "aflatoxin B1 (AFB1), dietary exposure, liver cancer risk, total aflatoxins (AFT)",
author = "Chin, {C. K.} and Aminah Abdullah and Y. Sugita-Konishi",
year = "2012",
month = "12",
doi = "10.1080/19393210.2012.713028",
language = "English",
volume = "5",
pages = "286--294",
journal = "Food Additives and Contaminants: Part B Surveillance",
issn = "1939-3210",
publisher = "Taylor and Francis Ltd.",
number = "4",

}

TY - JOUR

T1 - Dietary intake of aflatoxins in the adult Malaysian population - an assessment of risk

AU - Chin, C. K.

AU - Abdullah, Aminah

AU - Sugita-Konishi, Y.

PY - 2012/12

Y1 - 2012/12

N2 - Exposure to aflatoxins in the adult Malaysian diet was estimated by analysing aflatoxins in 236 food composites prepared as "ready for consumption". Dietary exposure to aflatoxin B1 (AFB1) ranged from 24.3 to 34.00 ng/kg b.w./day (lower to upper bound), with peanuts being the main contributor. Estimated liver cancer risk from this exposure was 0.61-0.85 cancers/100,000 population/year, contributing 12.4%-17.3% of the liver cancer cases. Excluding AFB1 occurrence data higher than 15 μg/kg reduced exposure by 65%-91% to 2.27-11.99 ng/kg b.w./day, reducing the cancer risk to 0.06-0.30 cancers/100,000 population/year (contributing 1.2%-6.1% liver cancer cases). Reducing further the ML of AFB1 from 15 to 5 μg/kg yielded 3%-7% greater drop in the exposure to 0.47-10.26 ng/kg b.w./day with an estimated risk of 0.01-0.26 cancers/100,000 population/year (0.2%-5.1% liver cancer cases attributed to dietary AFB1). These findings indicate that current MLs are adequate in protecting Malaysians' health.

AB - Exposure to aflatoxins in the adult Malaysian diet was estimated by analysing aflatoxins in 236 food composites prepared as "ready for consumption". Dietary exposure to aflatoxin B1 (AFB1) ranged from 24.3 to 34.00 ng/kg b.w./day (lower to upper bound), with peanuts being the main contributor. Estimated liver cancer risk from this exposure was 0.61-0.85 cancers/100,000 population/year, contributing 12.4%-17.3% of the liver cancer cases. Excluding AFB1 occurrence data higher than 15 μg/kg reduced exposure by 65%-91% to 2.27-11.99 ng/kg b.w./day, reducing the cancer risk to 0.06-0.30 cancers/100,000 population/year (contributing 1.2%-6.1% liver cancer cases). Reducing further the ML of AFB1 from 15 to 5 μg/kg yielded 3%-7% greater drop in the exposure to 0.47-10.26 ng/kg b.w./day with an estimated risk of 0.01-0.26 cancers/100,000 population/year (0.2%-5.1% liver cancer cases attributed to dietary AFB1). These findings indicate that current MLs are adequate in protecting Malaysians' health.

KW - aflatoxin B1 (AFB1)

KW - dietary exposure

KW - liver cancer risk

KW - total aflatoxins (AFT)

UR - http://www.scopus.com/inward/record.url?scp=84868242418&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868242418&partnerID=8YFLogxK

U2 - 10.1080/19393210.2012.713028

DO - 10.1080/19393210.2012.713028

M3 - Article

VL - 5

SP - 286

EP - 294

JO - Food Additives and Contaminants: Part B Surveillance

JF - Food Additives and Contaminants: Part B Surveillance

SN - 1939-3210

IS - 4

ER -