Dielectrophoresis: Characterization of triple-negative breast cancer using clausius-mossotti factor

Nur Mas Ayu Jamaludin, Muhamad Ramdzan Buyong, Muhammad Khairulanwar Abdul Rahim, Azrul Azlan Hamzah, Burhanuddin Yeon Mailis, Badariah Bais

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper describes a new possible application of dielectrophoresis (DEP) in breast cancer detection. Breast cancer is one of the most common cancer diseases in Malaysia which makes 17.7% of all cases reported between 2007 and 2011. This research aims to determine the dielectric properties of biophysical and biochemical of triple-negative breast cancer (TNBC). The manipulation of TNBC will be on the detection and enumeration based on polarization factor between permittivity and conductivity of TNBC and suspended medium. The results of analytical modelling prove that there are dynamic changes in the dielectric values, which are the permittivity and conductivity values between TNBC cell and medium when the frequency input value is changed. The findings offer a framework for anticipating TNBC dielectric detection response on the basis of structure-function relationship and suggest that dielectrophoresis lab-on-chip (DLOC) application for TNBC detection and enumeration should be widely used as a surface marker-independent method and provide high precision analysis in cancer progression and treatment effectiveness.

Original languageEnglish
Title of host publication2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages85-88
Number of pages4
Volume2018-August
ISBN (Electronic)9781538652831
DOIs
Publication statusPublished - 3 Oct 2018
Event13th IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Kuala Lumpur, Malaysia
Duration: 15 Aug 201817 Aug 2018

Other

Other13th IEEE International Conference on Semiconductor Electronics, ICSE 2018
CountryMalaysia
CityKuala Lumpur
Period15/8/1817/8/18

Fingerprint

Electrophoresis
Permittivity
Dielectric properties
Polarization

Keywords

  • Clausius-Mossotti factor
  • dielectric dynamic change
  • dielectrophoresis
  • triple-negative breast cancer

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Jamaludin, N. M. A., Buyong, M. R., Rahim, M. K. A., Hamzah, A. A., Mailis, B. Y., & Bais, B. (2018). Dielectrophoresis: Characterization of triple-negative breast cancer using clausius-mossotti factor. In 2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings (Vol. 2018-August, pp. 85-88). [8481322] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMELEC.2018.8481322

Dielectrophoresis : Characterization of triple-negative breast cancer using clausius-mossotti factor. / Jamaludin, Nur Mas Ayu; Buyong, Muhamad Ramdzan; Rahim, Muhammad Khairulanwar Abdul; Hamzah, Azrul Azlan; Mailis, Burhanuddin Yeon; Bais, Badariah.

2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings. Vol. 2018-August Institute of Electrical and Electronics Engineers Inc., 2018. p. 85-88 8481322.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jamaludin, NMA, Buyong, MR, Rahim, MKA, Hamzah, AA, Mailis, BY & Bais, B 2018, Dielectrophoresis: Characterization of triple-negative breast cancer using clausius-mossotti factor. in 2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings. vol. 2018-August, 8481322, Institute of Electrical and Electronics Engineers Inc., pp. 85-88, 13th IEEE International Conference on Semiconductor Electronics, ICSE 2018, Kuala Lumpur, Malaysia, 15/8/18. https://doi.org/10.1109/SMELEC.2018.8481322
Jamaludin NMA, Buyong MR, Rahim MKA, Hamzah AA, Mailis BY, Bais B. Dielectrophoresis: Characterization of triple-negative breast cancer using clausius-mossotti factor. In 2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings. Vol. 2018-August. Institute of Electrical and Electronics Engineers Inc. 2018. p. 85-88. 8481322 https://doi.org/10.1109/SMELEC.2018.8481322
Jamaludin, Nur Mas Ayu ; Buyong, Muhamad Ramdzan ; Rahim, Muhammad Khairulanwar Abdul ; Hamzah, Azrul Azlan ; Mailis, Burhanuddin Yeon ; Bais, Badariah. / Dielectrophoresis : Characterization of triple-negative breast cancer using clausius-mossotti factor. 2018 IEEE International Conference on Semiconductor Electronics, ICSE 2018 - Proceedings. Vol. 2018-August Institute of Electrical and Electronics Engineers Inc., 2018. pp. 85-88
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