Development of phase detection schemes based on surface plasmon resonance using interferometry

Muhammad Kashif, Ahmad Ashrif A. Bakar, Norhana Arsad, Sahbudin Shaari

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Surface plasmon resonance (SPR) is a novel optical sensing technique with a unique ability to monitor molecular binding in real-time for biological and chemical sensor applications. Interferometry is an excellent tool for accurate measurement of SPR changes, the measurement and comparison is made for the sensitivity, dynamic range and resolution of the different analytes using interferometry techniques. SPR interferometry can also employ phase detection in addition to the amplitude of the reflected light wave, and the phase changes more rapidly compared with other approaches, i.e., intensity, angle and wavelength. Therefore, the SPR phase interferometer offers the advantages of spatial phase resolution and high sensitivity. This work discusses the advancements in interferometric SPR methods to measure the phase shifts due to refractive index changes. The main application areas of SPR sensors are demonstrated, i.e., the Fabry-Perot interferometer, Michelson interferometer and Mach-Zehnder interferometer, with different configurations. The three interferometers are discussed in detail, and solutions are suggested to enhance the performance parameters that will aid in future biological and chemical sensors.

Original languageEnglish
Pages (from-to)15914-15938
Number of pages25
JournalSensors (Basel, Switzerland)
Volume14
Issue number9
DOIs
Publication statusPublished - 2014

Fingerprint

Interferometry
Surface Plasmon Resonance
Surface plasmon resonance
surface plasmon resonance
interferometry
Chemical sensors
Interferometers
sensors
interferometers
Fabry-Perot interferometers
Michelson interferometers
Refractometry
Mach-Zehnder interferometers
sensitivity
Phase shift
dynamic range
Refractive index
phase shift
refractivity
Light

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Development of phase detection schemes based on surface plasmon resonance using interferometry. / Kashif, Muhammad; Bakar, Ahmad Ashrif A.; Arsad, Norhana; Shaari, Sahbudin.

In: Sensors (Basel, Switzerland), Vol. 14, No. 9, 2014, p. 15914-15938.

Research output: Contribution to journalArticle

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