Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.

S. Sulaiman, N. Adeeb, N. Muslim, N. Adeeb, C. M. Ho

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    Determinations of total calcium, total magnesium, calcium ion, parathyroid hormone and 6-keto-prostaglandin-F1 alpha levels were carried out on 84 blood samples from 4 groups of women categorised as non-pregnant normotensive (NNP), pregnant normotensive (NP), pregnancy-induced hypertension (PIH) and pre-eclampsia (PE). PIH was clinically diagnosed when the diastolic pressure was more than 90 mmHg and was only hypertensive during pregnancy while PE was with additional proteinuria after 20 weeks of gestation. Compared to NNP women, total calcium and parathyroid hormone levels were of lower levels (p < 0.05) in NP women while in PIH women, total calcium and 6-keto-prostaglandin-F1 alpha levels were also lowered (p < 0.05). Compared to NNP women, PE women's levels of total calcium, calcium ion and 6-keto-prostaglandin-F1 alpha decreased (p < 0.05) while parathyroid hormone level increased (p < 0.05). When compared to the NP women, PE women had decreased levels (p < 0.05) of total calcium as well as calcium ion and increased level (p < 0.05) of parathyroid hormone. Calcium ion was found to be negatively correlated (NNP : r = -0.883, p = 0.008/NP : r = -0.931, p = 0.000) while parathyroid hormone was positively correlated (NNP : r = 0.904, p = 0.013/NP : r = 0.913, p = 0.000) with mean arterial pressure.

    Original languageEnglish
    Pages (from-to)637-640
    Number of pages4
    JournalSingapore Medical Journal
    Volume36
    Issue number6
    Publication statusPublished - Dec 1995

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    Pre-Eclampsia
    Parathyroid Hormone
    Minerals
    Pregnant Women
    Hypertension
    Calcium
    Pregnancy Induced Hypertension
    Ions
    prostaglandin F1
    Pregnancy
    Proteinuria
    Magnesium
    Arterial Pressure
    Blood Pressure

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia. / Sulaiman, S.; Adeeb, N.; Muslim, N.; Adeeb, N.; Ho, C. M.

    In: Singapore Medical Journal, Vol. 36, No. 6, 12.1995, p. 637-640.

    Research output: Contribution to journalArticle

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