Determination of malathion levels and the effect of malathion on the growth of Chrysomya megacephala (Fibricius) in malathion-exposed rat carcass

Rumiza Abd Rashid, Khairul Osman, Mohd Iswadi Ismail, Raja Muhammad Zuha Raja Kamal Bashah, Rogayah Abu Hassan

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

This study was conducted to examine the effect of malathion on the development of Chrysomya megacephala. A total of 12 adult Sprague-Dawley rats was divided into 4 groups. Each animal in the 4 groups was given orally 0 (control), 10, 25 and 50ml/kg body weight of malathion, respectively. Chrysomya megacephala larvae were then allowed to grow on the liver of carcass. Larvae development was estimated by means of weight and length, time of adult emergence and survival rate. Results indicated that for the first 6 to 30 hours, larvae from control group developed more rapidly than larvae feeding on tissue containing malathion. However, the 3 doses of malathion did not exhibit significant impact on larvae length and weight. The time required for adult emergence was significantly greater for malathion-treated colony which was 10 days compared to 7 days in control colony. Control larvae of C. megacephala had higher survival rate compared to larvae exposed to the three different doses of malathion. Analysis of the tissues indicated that all rats and fly samples were positive for malathion. Malathion concentration was highest in liver. It was concluded that the presence of malathion altered the development rate of C. megacephala and thus disrupted normal postmortem interval estimation.

Original languageEnglish
Pages (from-to)184-190
Number of pages7
JournalTropical Biomedicine
Volume25
Issue number3
Publication statusPublished - 2008

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Malathion
Larva
Growth
Weights and Measures
Liver
Diptera
Sprague Dawley Rats
Body Weight
Control Groups

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology
  • Medicine(all)

Cite this

Determination of malathion levels and the effect of malathion on the growth of Chrysomya megacephala (Fibricius) in malathion-exposed rat carcass. / Rashid, Rumiza Abd; Osman, Khairul; Ismail, Mohd Iswadi; Raja Kamal Bashah, Raja Muhammad Zuha; Hassan, Rogayah Abu.

In: Tropical Biomedicine, Vol. 25, No. 3, 2008, p. 184-190.

Research output: Contribution to journalArticle

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