Design and numerical investigation of porous nanocrystalline silicon membrane filtration device for artificial kidney

Muhammad Fahmi Jaafar, Wan Ammar Fikri Wan Ali, Burhanuddin Yeop Majlis, Jumril Yunas, Rhonira Latif

Research output: Contribution to journalArticle

Abstract

A micro-filtration device consists of a free standing porous nanocrystalline silicon membrane in between two flowing fluid channels is designed to mimic the filtration process in human kidney. The fluid velocity profile, membrane filtration rate, channel’s filtration pressure field and filtrate concentration distribution surrounding the membrane are numerically investigated for a wide range of top channel pressure, membrane thickness, membrane width and channel thickness. The optimised device geometry working at 150 mmHg has been found to be capable of delivering the required minimum filtration rate targeted for continuous filtration in artificial kidney. The maximum fluid pressure exerted on the membrane has been simulated to be ∼50% smaller than the experimental limit of the applied pressure that a pnc-Si membrane can withhold without breaking. The numerical investigation can assist the fabrication design of an optimised pnc-Si membrane device for artificial kidney.

Original languageEnglish
Pages (from-to)2695-2703
Number of pages9
JournalJournal of Computational and Theoretical Nanoscience
Volume16
Issue number7
DOIs
Publication statusPublished - 1 Jan 2019

Fingerprint

Nanocrystalline silicon
Porous silicon
Kidney
kidneys
Numerical Investigation
Filtration
Silicon
Membrane
membranes
Membranes
silicon
Fluids
Fluid
Microfiltration
fluid pressure
Design
fluids
Ion Channels
Velocity Profile
pressure distribution

Keywords

  • Artificial Kidney
  • Filtration Membrane
  • Flow Rate
  • Numerical Simulations
  • Porous Nanocrystalline Silicon

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Computational Mathematics
  • Electrical and Electronic Engineering

Cite this

Design and numerical investigation of porous nanocrystalline silicon membrane filtration device for artificial kidney. / Jaafar, Muhammad Fahmi; Ali, Wan Ammar Fikri Wan; Majlis, Burhanuddin Yeop; Yunas, Jumril; Latif, Rhonira.

In: Journal of Computational and Theoretical Nanoscience, Vol. 16, No. 7, 01.01.2019, p. 2695-2703.

Research output: Contribution to journalArticle

@article{31d86c3171b44562bba2d54dc7addada,
title = "Design and numerical investigation of porous nanocrystalline silicon membrane filtration device for artificial kidney",
abstract = "A micro-filtration device consists of a free standing porous nanocrystalline silicon membrane in between two flowing fluid channels is designed to mimic the filtration process in human kidney. The fluid velocity profile, membrane filtration rate, channel’s filtration pressure field and filtrate concentration distribution surrounding the membrane are numerically investigated for a wide range of top channel pressure, membrane thickness, membrane width and channel thickness. The optimised device geometry working at 150 mmHg has been found to be capable of delivering the required minimum filtration rate targeted for continuous filtration in artificial kidney. The maximum fluid pressure exerted on the membrane has been simulated to be ∼50{\%} smaller than the experimental limit of the applied pressure that a pnc-Si membrane can withhold without breaking. The numerical investigation can assist the fabrication design of an optimised pnc-Si membrane device for artificial kidney.",
keywords = "Artificial Kidney, Filtration Membrane, Flow Rate, Numerical Simulations, Porous Nanocrystalline Silicon",
author = "Jaafar, {Muhammad Fahmi} and Ali, {Wan Ammar Fikri Wan} and Majlis, {Burhanuddin Yeop} and Jumril Yunas and Rhonira Latif",
year = "2019",
month = "1",
day = "1",
doi = "10.1166/jctn.2019.8231",
language = "English",
volume = "16",
pages = "2695--2703",
journal = "Journal of Computational and Theoretical Nanoscience",
issn = "1546-1955",
publisher = "American Scientific Publishers",
number = "7",

}

TY - JOUR

T1 - Design and numerical investigation of porous nanocrystalline silicon membrane filtration device for artificial kidney

AU - Jaafar, Muhammad Fahmi

AU - Ali, Wan Ammar Fikri Wan

AU - Majlis, Burhanuddin Yeop

AU - Yunas, Jumril

AU - Latif, Rhonira

PY - 2019/1/1

Y1 - 2019/1/1

N2 - A micro-filtration device consists of a free standing porous nanocrystalline silicon membrane in between two flowing fluid channels is designed to mimic the filtration process in human kidney. The fluid velocity profile, membrane filtration rate, channel’s filtration pressure field and filtrate concentration distribution surrounding the membrane are numerically investigated for a wide range of top channel pressure, membrane thickness, membrane width and channel thickness. The optimised device geometry working at 150 mmHg has been found to be capable of delivering the required minimum filtration rate targeted for continuous filtration in artificial kidney. The maximum fluid pressure exerted on the membrane has been simulated to be ∼50% smaller than the experimental limit of the applied pressure that a pnc-Si membrane can withhold without breaking. The numerical investigation can assist the fabrication design of an optimised pnc-Si membrane device for artificial kidney.

AB - A micro-filtration device consists of a free standing porous nanocrystalline silicon membrane in between two flowing fluid channels is designed to mimic the filtration process in human kidney. The fluid velocity profile, membrane filtration rate, channel’s filtration pressure field and filtrate concentration distribution surrounding the membrane are numerically investigated for a wide range of top channel pressure, membrane thickness, membrane width and channel thickness. The optimised device geometry working at 150 mmHg has been found to be capable of delivering the required minimum filtration rate targeted for continuous filtration in artificial kidney. The maximum fluid pressure exerted on the membrane has been simulated to be ∼50% smaller than the experimental limit of the applied pressure that a pnc-Si membrane can withhold without breaking. The numerical investigation can assist the fabrication design of an optimised pnc-Si membrane device for artificial kidney.

KW - Artificial Kidney

KW - Filtration Membrane

KW - Flow Rate

KW - Numerical Simulations

KW - Porous Nanocrystalline Silicon

UR - http://www.scopus.com/inward/record.url?scp=85073100453&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85073100453&partnerID=8YFLogxK

U2 - 10.1166/jctn.2019.8231

DO - 10.1166/jctn.2019.8231

M3 - Article

AN - SCOPUS:85073100453

VL - 16

SP - 2695

EP - 2703

JO - Journal of Computational and Theoretical Nanoscience

JF - Journal of Computational and Theoretical Nanoscience

SN - 1546-1955

IS - 7

ER -