Dengue in Malaysia: An epidemiological perspective Study

Muhammad Hasyim Chew, Md. Mostafizur Rahman, Sharifah Azura Salleh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objectives: Dengue is a mosquito-transmitted infection and is an important health problem in Asia for its fatality. The objective of the study was to determine some epidemiological parameters relating to age, gender, community, and prevalence nature, serology and disease severity. Methodology: One hundred forty nine dengue suspected sera samples were obtained from suspected patients presenting with dengue symptoms. The samples collected were analyzed by serological detection of Immunoglobulin-M (IgM), Immunoglobulin G (IgG), virus culture in cellline C36/36 and Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Results: The studies showed that out of 149 sera samples, 48 (32.2%) were detected dengue virus by cell culture and RT-PCR and 108 (72.5%) positive by serology. Of the 108 cases, 40 (26.8%) were positive to IgM, 61 (41%) were positive to both IgG and IgM, and 7(4.7%) cases were positive to IgG only. Prevalence of dengue was higher in age group 20-29 years and infection was more in male and in Malay population. Epidemic intensity was the highest in the month of June. Conclusions: Dengue is highly endemic in Malaysia and age group 20-29 was vulnerable to infection, male infected more than female and infection was higher in Malay community. Effective preventive and control measures may be strengthened to reduce the infections.

Original languageEnglish
JournalPakistan Journal of Medical Sciences
Volume28
Issue number4
Publication statusPublished - Jul 2012

Fingerprint

Dengue
Malaysia
Epidemiologic Studies
Immunoglobulin M
Infection
Immunoglobulin G
Serology
Reverse Transcriptase Polymerase Chain Reaction
Age Groups
Dengue Virus
Culicidae
Serum
Cell Culture Techniques
Viruses
Health
Population

Keywords

  • Dengue virus
  • Epidemology
  • IgG
  • RT-PCR
  • Serology igM

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dengue in Malaysia : An epidemiological perspective Study. / Chew, Muhammad Hasyim; Rahman, Md. Mostafizur; Salleh, Sharifah Azura.

In: Pakistan Journal of Medical Sciences, Vol. 28, No. 4, 07.2012.

Research output: Contribution to journalArticle

Chew, Muhammad Hasyim ; Rahman, Md. Mostafizur ; Salleh, Sharifah Azura. / Dengue in Malaysia : An epidemiological perspective Study. In: Pakistan Journal of Medical Sciences. 2012 ; Vol. 28, No. 4.
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