Definition and comparison of a new vascular index between young healthy and aged subjects

Rosmina Jaafar, Edmond Zahedi, Mohd Alauddin Mohd Ali

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In an effort to identify a useful noninvasive screening tool for cardiovascular diseases (CVD) screening, photoplethysmograph (PPG) signals were acquired and analyzed. These PPG signals were recorded during reactive hyperemia experiments consisting of a 4-minute blood flow blockage of the right arm (RA) brachial artery (BA) using a blood pressure cuff inflator. This procedure is usually done for the assessment of endothelial dysfunction which is a risk factor for developing CVD. In this study, signals of the infrared (IR) and red (R) LED's of the PPG sensor were analyzed. These signals were preprocessed, normalized and slow varying component of the signal (DC values) and the pulsatile component (AC values) were extracted and evaluated for peak response during the reactive hyperemia after the release of blood flow blockage. PPG data of five healthy young female individuals (mean age 32.0 ± 1.6 years) were compared to that of five aged female individuals (mean age 64.0 ± 2.9 years). Results show that the IR PPG signals behave similarly to that of the R PPG signals (AC and DC) for both study groups. The young healthy subjects peak AC-IR and peak AC-R are significantly smaller than that of the aged subjects, (4.0 ± 2.4 versus 9.3 ± 5.0, p-value 0.06) and (2.0 ± 1.3 versus 5.4 ± 2.5, p-value 0.03), respectively. Nevertheless, the peak DC-R for the young subjects is significantly higher than that of the aged subjects (23.4 ± 8.3 versus 11.8 ± 6.3, p-value 0.04). The time to reach the peak points is not significantly different between the groups, which confirms our previous study. Since this optical technique is non-invasive and low-cost, it could be ultimately performed in routine clinical setting for the screening of endothelial dysfunction disorders.

Original languageEnglish
Title of host publicationIECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet"
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages911-915
Number of pages5
ISBN (Print)9781479940844
DOIs
Publication statusPublished - 23 Feb 2015
Event3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014 - Kuala Lumpur
Duration: 8 Dec 201410 Dec 2014

Other

Other3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014
CityKuala Lumpur
Period8/12/1410/12/14

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Screening
Infrared radiation
Blood
Blood pressure
Light emitting diodes
Sensors
Costs
Experiments

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Jaafar, R., Zahedi, E., & Mohd Ali, M. A. (2015). Definition and comparison of a new vascular index between young healthy and aged subjects. In IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet" (pp. 911-915). [7047644] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IECBES.2014.7047644

Definition and comparison of a new vascular index between young healthy and aged subjects. / Jaafar, Rosmina; Zahedi, Edmond; Mohd Ali, Mohd Alauddin.

IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc., 2015. p. 911-915 7047644.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jaafar, R, Zahedi, E & Mohd Ali, MA 2015, Definition and comparison of a new vascular index between young healthy and aged subjects. in IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet"., 7047644, Institute of Electrical and Electronics Engineers Inc., pp. 911-915, 3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014, Kuala Lumpur, 8/12/14. https://doi.org/10.1109/IECBES.2014.7047644
Jaafar R, Zahedi E, Mohd Ali MA. Definition and comparison of a new vascular index between young healthy and aged subjects. In IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc. 2015. p. 911-915. 7047644 https://doi.org/10.1109/IECBES.2014.7047644
Jaafar, Rosmina ; Zahedi, Edmond ; Mohd Ali, Mohd Alauddin. / Definition and comparison of a new vascular index between young healthy and aged subjects. IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc., 2015. pp. 911-915
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