Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data

Hong Sheng Wang, Suthipong Sthiannopkao, Jun Du, Zhuo Jia Chen, Kyoung Woong Kim, Mohamed Salleh Mohamed Yasin, Jamal Hisham Hashim, Chris Kong Chu Wong, Ming Hung Wong

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

To assess organochlorine pesticide (OCP) contaminations and its possible adverse health impacts, different food samples were collected from three areas of Cambodia, one of the poorest countries in the world. The ∑OCP concentrations in Kampong Cham, Kratie and Kandal provinces ranged from 1.28 to 188 (median 3.11), 1.06 to 25.1 (5.59) and 2.20 to 103 (20.6)ngg -1, respectively. The dichlorodiphenyltrichloroethanes (DDTs) were the predominant OCPs and accounted for 62.2% (median) among all foodstuffs. Congener profile analyses suggested that there were new input sources of DDTs and hexachlorocyclohexanes (HCHs) in Cambodia, particularly in Kandal province. The estimated daily intake of OCPs (330ngkg -1day -1) for residents in Kandal province ranked No. 1 among the 13 compared countries or regions. On the basis of 95th percentile concentrations, the carcinogenic hazard ratios (HRs) of most investigated individual OCPs in vegetable and fish in Cambodia exceeding unity. Particularly for α-HCH in vegetable, the 95th HR was as high as 186. The data revealed that there is a great cancer risk for the local residents with life time consumption of OCP contaminated vegetable and fish. To our knowledge, this the first study to evaluate the daily intakes of OCPs in Cambodia.

Original languageEnglish
Pages (from-to)1441-1449
Number of pages9
JournalJournal of Hazardous Materials
Volume192
Issue number3
DOIs
Publication statusPublished - 15 Sep 2011
Externally publishedYes

Fingerprint

Pesticides
Risk assessment
risk assessment
Cambodia
market
Vegetables
vegetable
Lindane
HCH
DDT
Fish
Hazards
Fishes
hazard
health impact
fish
organochlorine pesticide
Contamination
Health
Food

Keywords

  • Cambodia
  • Daily intake
  • Food consumption
  • Organochlorine pesticides (OCPs)
  • Risk assessment

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Pollution
  • Waste Management and Disposal
  • Environmental Chemistry
  • Environmental Engineering

Cite this

Wang, H. S., Sthiannopkao, S., Du, J., Chen, Z. J., Kim, K. W., Mohamed Yasin, M. S., ... Wong, M. H. (2011). Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data. Journal of Hazardous Materials, 192(3), 1441-1449. https://doi.org/10.1016/j.jhazmat.2011.06.062

Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data. / Wang, Hong Sheng; Sthiannopkao, Suthipong; Du, Jun; Chen, Zhuo Jia; Kim, Kyoung Woong; Mohamed Yasin, Mohamed Salleh; Hashim, Jamal Hisham; Wong, Chris Kong Chu; Wong, Ming Hung.

In: Journal of Hazardous Materials, Vol. 192, No. 3, 15.09.2011, p. 1441-1449.

Research output: Contribution to journalArticle

Wang, HS, Sthiannopkao, S, Du, J, Chen, ZJ, Kim, KW, Mohamed Yasin, MS, Hashim, JH, Wong, CKC & Wong, MH 2011, 'Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data', Journal of Hazardous Materials, vol. 192, no. 3, pp. 1441-1449. https://doi.org/10.1016/j.jhazmat.2011.06.062
Wang, Hong Sheng ; Sthiannopkao, Suthipong ; Du, Jun ; Chen, Zhuo Jia ; Kim, Kyoung Woong ; Mohamed Yasin, Mohamed Salleh ; Hashim, Jamal Hisham ; Wong, Chris Kong Chu ; Wong, Ming Hung. / Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data. In: Journal of Hazardous Materials. 2011 ; Vol. 192, No. 3. pp. 1441-1449.
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