Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii

Muhtadi, Euis H. Hakim, Lia D. Juliawaty, Yana M. Syah, Sjamsul A. Achmad, Jalifah Latip, Emilio L. Ghisalberti

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

A new resveratrol tetramer, named diptoindonesin E, was isolated from the acetone extract of the tree bark of Dipterocarpus hasseltii, together with five known resveratrol oligomers (-)-ε-viniferin, laevifonol, (-)-α-viniferin, vaticanol B, (-)-hopeaphenol, and a coumarin, scopoletin. The structures of these compounds were determined from spectroscopic evidence. Cytotoxicity test of the isolated compounds showed that hopeaphenol strongly inhibited murine leukemia P-388 cells.

Original languageEnglish
Pages (from-to)550-555
Number of pages6
JournalFitoterapia
Volume77
Issue number7-8
DOIs
Publication statusPublished - Dec 2006

Fingerprint

Plant Bark
Scopoletin
Acetone
Leukemia
resveratrol
hopeaphenol

Keywords

  • Dipterocarpus hasseltii
  • Diptoindonesin E
  • Murine leukemia P-388 cells
  • Oligomer resveratrol

ASJC Scopus subject areas

  • Pharmacology

Cite this

Muhtadi, Hakim, E. H., Juliawaty, L. D., Syah, Y. M., Achmad, S. A., Latip, J., & Ghisalberti, E. L. (2006). Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii. Fitoterapia, 77(7-8), 550-555. https://doi.org/10.1016/j.fitote.2006.07.004

Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii. / Muhtadi; Hakim, Euis H.; Juliawaty, Lia D.; Syah, Yana M.; Achmad, Sjamsul A.; Latip, Jalifah; Ghisalberti, Emilio L.

In: Fitoterapia, Vol. 77, No. 7-8, 12.2006, p. 550-555.

Research output: Contribution to journalArticle

Muhtadi, Hakim, EH, Juliawaty, LD, Syah, YM, Achmad, SA, Latip, J & Ghisalberti, EL 2006, 'Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii', Fitoterapia, vol. 77, no. 7-8, pp. 550-555. https://doi.org/10.1016/j.fitote.2006.07.004
Muhtadi ; Hakim, Euis H. ; Juliawaty, Lia D. ; Syah, Yana M. ; Achmad, Sjamsul A. ; Latip, Jalifah ; Ghisalberti, Emilio L. / Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii. In: Fitoterapia. 2006 ; Vol. 77, No. 7-8. pp. 550-555.
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