Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides

Sahidin, Euis H. Hakim, Lia D. Juliawaty, Yana M. Syah, Laily Bin Din, Emilio L. Ghisalberti, Jalifah Latip, Ikram M. Said, Sjamsul A. Achmad

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

A new modified stilbene dimer, diptoindonesin D (1), was isolated from the acetone extract of the tree bark of Hopea dryobalanoides, together with seven known compounds, parviflorol (2), (-)-balanocarpol (3), heimiol A (4), hopeafuran (5), (+)-α-viniferin (6), vaticanol B (7) and (-)-hopeaphenol (8). Cytotoxic properties of compounds 1-8 were evaluated against murine leukemia P-388 cells. Compound 8 was found to be the most active with IC 50 of 5.7 μM.

Original languageEnglish
Pages (from-to)723-727
Number of pages5
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume60
Issue number9-10
Publication statusPublished - Sep 2005

Fingerprint

Dipterocarpaceae
Plant Bark
Hopea
viniferins
Stilbenes
stilbenes
Acetone
leukemia
Dimers
acetone
inhibitory concentration 50
Leukemia
bark
mice
extracts
cells
heimiol A
hopeafuran
8-1 compound
Vaticanol B

Keywords

  • Diptoindonesin D
  • Hopea dryobalanoides
  • Murine Leukemia P-388 Cells

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

Sahidin, Hakim, E. H., Juliawaty, L. D., Syah, Y. M., Din, L. B., Ghisalberti, E. L., ... Achmad, S. A. (2005). Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 60(9-10), 723-727.

Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides. / Sahidin; Hakim, Euis H.; Juliawaty, Lia D.; Syah, Yana M.; Din, Laily Bin; Ghisalberti, Emilio L.; Latip, Jalifah; Said, Ikram M.; Achmad, Sjamsul A.

In: Zeitschrift fur Naturforschung - Section C Journal of Biosciences, Vol. 60, No. 9-10, 09.2005, p. 723-727.

Research output: Contribution to journalArticle

Sahidin, Hakim, EH, Juliawaty, LD, Syah, YM, Din, LB, Ghisalberti, EL, Latip, J, Said, IM & Achmad, SA 2005, 'Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides', Zeitschrift fur Naturforschung - Section C Journal of Biosciences, vol. 60, no. 9-10, pp. 723-727.
Sahidin, Hakim EH, Juliawaty LD, Syah YM, Din LB, Ghisalberti EL et al. Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides. Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 2005 Sep;60(9-10):723-727.
Sahidin ; Hakim, Euis H. ; Juliawaty, Lia D. ; Syah, Yana M. ; Din, Laily Bin ; Ghisalberti, Emilio L. ; Latip, Jalifah ; Said, Ikram M. ; Achmad, Sjamsul A. / Cytotoxic properties of oligostilbenoids from the tree barks of Hopea dryobalanoides. In: Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 2005 ; Vol. 60, No. 9-10. pp. 723-727.
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