Current knowledge of metabolomic approach in infectious fish disease studies

Low Chen Fei, M. Z.H. Rozaini, N. Musa, Syarul Nataqain Baharum

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

The approaches of transcriptomic and proteomic have been widely used to study host–pathogen interactions in fish diseases, and this is comparable to the recently emerging application of metabolomic in elucidating disease-resistant mechanisms in fish that gives new insight into potential therapeutic strategies to improve fish health. Metabolomic is defined as the large-scale study of all metabolites within an organism and represents the frontline in the ‘omics’ approaches, providing direct information on the metabolic responses and perturbations in metabolic pathways. In this review, the current research in infectious fish diseases using metabolomic approach will be summarized. The metabolomic approach in economically important fish infected with viruses, bacteria and nematodes will also be discussed. The potential of the metabolomic approach for management of these infectious diseases as well as the challenges and the limitations of metabolomic in fish disease studies will be explored. Current review highlights the impacts of metabolomic studies in infectious fish diseases, which proposed the potential of new therapeutic strategies to enhance disease resistance in fish.

Original languageEnglish
Pages (from-to)1267-1277
Number of pages11
JournalJournal of Fish Diseases
Volume40
Issue number10
DOIs
Publication statusPublished - 1 Oct 2017

Fingerprint

Fish Diseases
fish diseases
Metabolomics
metabolomics
Communicable Diseases
Fishes
fish
disease resistance
proteomics
infectious disease
fish health
therapeutics
nematode
Disease Resistance
metabolite
virus
perturbation
Metabolic Networks and Pathways
fish disease
transcriptomics

Keywords

  • infectious fish diseases
  • metabolomic
  • systems biology

ASJC Scopus subject areas

  • Aquatic Science
  • veterinary (miscalleneous)

Cite this

Current knowledge of metabolomic approach in infectious fish disease studies. / Chen Fei, Low; Rozaini, M. Z.H.; Musa, N.; Baharum, Syarul Nataqain.

In: Journal of Fish Diseases, Vol. 40, No. 10, 01.10.2017, p. 1267-1277.

Research output: Contribution to journalReview article

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