Abstract
Cryptococcal meningitis is a fatal central nervous system disease commonly affecting immunocompromised patients, and rarely affects immunocompetent patients. We report a 51-year-old previously well male who presented with giddiness, altered sensorium and intermittent fever. India Ink stain and cryptococcal antigen test of cerebral spinal fluid were both positive. Immunodeficiency screening was negative. Although MRI brain demonstrated several features that are characteristic, they are unfortunately non-specific. It is important to realise immunocompetence does not exclude one from contracting cryptococcal meningitis, and a high index of suspicion with consideration of various imaging differentials and biochemical markers is helpful in narrowing down the diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | TD01-TD02 |
| Journal | Journal of Clinical and Diagnostic Research |
| Volume | 12 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1 Jul 2018 |
| Externally published | Yes |
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Keywords
- Basal leptomeningeal enhancement
- Choroid plexus enlargement
- Hydrocephalus
- Periventricular cysts
ASJC Scopus subject areas
- Clinical Biochemistry
Cite this
Cryptococcal meningitis : Imaging findings in an immunocompetent patient. / Syazana, Ishak; Erica Yee Hing, Wong.
In: Journal of Clinical and Diagnostic Research, Vol. 12, No. 7, 01.07.2018, p. TD01-TD02.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cryptococcal meningitis
T2 - Imaging findings in an immunocompetent patient
AU - Syazana, Ishak
AU - Erica Yee Hing, Wong
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Cryptococcal meningitis is a fatal central nervous system disease commonly affecting immunocompromised patients, and rarely affects immunocompetent patients. We report a 51-year-old previously well male who presented with giddiness, altered sensorium and intermittent fever. India Ink stain and cryptococcal antigen test of cerebral spinal fluid were both positive. Immunodeficiency screening was negative. Although MRI brain demonstrated several features that are characteristic, they are unfortunately non-specific. It is important to realise immunocompetence does not exclude one from contracting cryptococcal meningitis, and a high index of suspicion with consideration of various imaging differentials and biochemical markers is helpful in narrowing down the diagnosis.
AB - Cryptococcal meningitis is a fatal central nervous system disease commonly affecting immunocompromised patients, and rarely affects immunocompetent patients. We report a 51-year-old previously well male who presented with giddiness, altered sensorium and intermittent fever. India Ink stain and cryptococcal antigen test of cerebral spinal fluid were both positive. Immunodeficiency screening was negative. Although MRI brain demonstrated several features that are characteristic, they are unfortunately non-specific. It is important to realise immunocompetence does not exclude one from contracting cryptococcal meningitis, and a high index of suspicion with consideration of various imaging differentials and biochemical markers is helpful in narrowing down the diagnosis.
KW - Basal leptomeningeal enhancement
KW - Choroid plexus enlargement
KW - Hydrocephalus
KW - Periventricular cysts
UR - http://www.scopus.com/inward/record.url?scp=85049530019&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049530019&partnerID=8YFLogxK
U2 - 10.7860/JCDR/2018/36215.11812
DO - 10.7860/JCDR/2018/36215.11812
M3 - Article
VL - 12
SP - TD01-TD02
JO - Journal of Clinical and Diagnostic Research
JF - Journal of Clinical and Diagnostic Research
SN - 0973-709X
IS - 7
ER -