Crevicular tartrate resistant acid phosphatase activity and rate of tooth movement under different continuous force applications

Rohaya Megat Abdul Wahab, Maryati Md Dasor, Sahidan Senafi, Asma Alhusna Abang Abdullah, Abdul Aziz Jemain, Nurfathiha Abu Kasim, Zulham Yamamoto, Shahrul Hisham Zainal Ariffin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This study investigated specific activities of tartrate resistant acid phosphatase (TRAP) in gingival crevicular fluid (GCF) and cumulative canine movement when two orthodontic forces were applied during orthodontic treatment. Each selected subjects (n = 12) randomly received a 100 and 150 g force for canine retraction either on the right or left site of maxillary arch. GCF was collected at the mesial and distal sites of the canines for 5 consecutive weeks where baseline activity served as control. Canine distance was measured before retraction and weekly (5 weeks) after force application. TRAP activity was determined using spectrophotometer. At the distal site of test canine (150 g force), TRAP activity peaked significantly (P < 0.05) at week 4 while tested canine (100 g force) at week 5. At the mesial site of test canine, no significant (P > 0.05) TRAP activities were found between 150 and 100 g of forces. There was significantly (P < 0.05) more cumulative canine movement by 5 weeks in 150 g as compared to 100 g force. TRAP enzyme can be a useful biomarker for monitoring orthodontic tooth movement. A force of 150 g was found to be more optimal in canine retraction than 100 g force.

Original languageEnglish
Pages (from-to)2213-2219
Number of pages7
JournalAfrican Journal of Pharmacy and Pharmacology
Volume5
Issue number20
DOIs
Publication statusPublished - 29 Nov 2011

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Tooth Movement Techniques
Canidae
Gingival Crevicular Fluid
Orthodontics
Tartrate-Resistant Acid Phosphatase
Biomarkers
Enzymes

Keywords

  • Biomarker
  • Bone remodeling
  • Orthodontic forces
  • Tartrate resistant acid phosphatase
  • Tooth movement

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

Cite this

Crevicular tartrate resistant acid phosphatase activity and rate of tooth movement under different continuous force applications. / Megat Abdul Wahab, Rohaya; Dasor, Maryati Md; Senafi, Sahidan; Abang Abdullah, Asma Alhusna; Jemain, Abdul Aziz; Kasim, Nurfathiha Abu; Yamamoto, Zulham; Zainal Ariffin, Shahrul Hisham.

In: African Journal of Pharmacy and Pharmacology, Vol. 5, No. 20, 29.11.2011, p. 2213-2219.

Research output: Contribution to journalArticle

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