Crevicular alkaline phosphatase activity during orthodontic tooth movement

Canine retraction stage

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

To observe pattern of ALP activity in Gingival Crevicular Fluid (GCF) during canine retraction stage of fixed orthodontic treatment. Ten patients age between 15 to 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. The tested canines were distalized using nickel titanium push coil spring. The level of ALP at week 0 acted as the baseline. Samples were taken at day 0, at week 1, 4, 8 and 12. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the differences at weekly interval and between test and control groups over the study period. The ALP level was decreased in both the mesial and distal of the test teeth for the first month and stabilizes months after. Significant difference were detected from week 4 upward when compared to the baseline (p<0.05). The bony turnover specifically the bone formation can be monitored through the expression of ALP in the gingival crevicular fluid during orthodontic treatment.

Original languageEnglish
Pages (from-to)228-233
Number of pages6
JournalJournal of Medical Sciences
Volume8
Issue number3
DOIs
Publication statusPublished - 1 Apr 2008

Fingerprint

Tooth Movement Techniques
Orthodontics
Gingival Crevicular Fluid
Alkaline Phosphatase
Canidae
Lip
Osteogenesis
Tooth
Control Groups
Therapeutics

Keywords

  • Alkaline phosphatase
  • Gingival crevicular fluid
  • Orthodontic

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Crevicular alkaline phosphatase activity during orthodontic tooth movement: Canine retraction stage",
abstract = "To observe pattern of ALP activity in Gingival Crevicular Fluid (GCF) during canine retraction stage of fixed orthodontic treatment. Ten patients age between 15 to 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. The tested canines were distalized using nickel titanium push coil spring. The level of ALP at week 0 acted as the baseline. Samples were taken at day 0, at week 1, 4, 8 and 12. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the differences at weekly interval and between test and control groups over the study period. The ALP level was decreased in both the mesial and distal of the test teeth for the first month and stabilizes months after. Significant difference were detected from week 4 upward when compared to the baseline (p<0.05). The bony turnover specifically the bone formation can be monitored through the expression of ALP in the gingival crevicular fluid during orthodontic treatment.",
keywords = "Alkaline phosphatase, Gingival crevicular fluid, Orthodontic",
author = "{Abang Abdullah}, {Asma Alhusna} and {Megat Abdul Wahab}, Rohaya and {Zainal Ariffin}, {Shahrul Hisham}",
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T2 - Canine retraction stage

AU - Abang Abdullah, Asma Alhusna

AU - Megat Abdul Wahab, Rohaya

AU - Zainal Ariffin, Shahrul Hisham

PY - 2008/4/1

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N2 - To observe pattern of ALP activity in Gingival Crevicular Fluid (GCF) during canine retraction stage of fixed orthodontic treatment. Ten patients age between 15 to 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. The tested canines were distalized using nickel titanium push coil spring. The level of ALP at week 0 acted as the baseline. Samples were taken at day 0, at week 1, 4, 8 and 12. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the differences at weekly interval and between test and control groups over the study period. The ALP level was decreased in both the mesial and distal of the test teeth for the first month and stabilizes months after. Significant difference were detected from week 4 upward when compared to the baseline (p<0.05). The bony turnover specifically the bone formation can be monitored through the expression of ALP in the gingival crevicular fluid during orthodontic treatment.

AB - To observe pattern of ALP activity in Gingival Crevicular Fluid (GCF) during canine retraction stage of fixed orthodontic treatment. Ten patients age between 15 to 27 years old with moderate upper labial segment crowding were recruited from postgraduate orthodontic clinic. The tested canines were distalized using nickel titanium push coil spring. The level of ALP at week 0 acted as the baseline. Samples were taken at day 0, at week 1, 4, 8 and 12. The activities of ALP were measured using spectrophotometer (405 nm). Paired sample t-test was used to assess the differences at weekly interval and between test and control groups over the study period. The ALP level was decreased in both the mesial and distal of the test teeth for the first month and stabilizes months after. Significant difference were detected from week 4 upward when compared to the baseline (p<0.05). The bony turnover specifically the bone formation can be monitored through the expression of ALP in the gingival crevicular fluid during orthodontic treatment.

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