Abstract
Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because of their diverse biological activity and clinical applications, they are remarkably effective compounds both with respect to their inhibitory activity and their favourable selectivity ratio. Coumarins are regarded as a promising class of bioactive heterocyclic compounds that exhibit a range of biological activities like anti-microbial, anti-viral, anti-diabetic, anti-cancer activity, anti-oxidant, anti-parasitic, anti-helmintic, anti-proliferative, anti-convulsant, anti-inflammatory and anti-hypertensive activities etc. The information given in this manuscript may be helpful in the further research of better antimicrobial agents having lesser microbial resistance and improved antimicrobial profile.
| Original language | English |
|---|---|
| Pages (from-to) | 62-70 |
| Number of pages | 9 |
| Journal | Systematic Reviews in Pharmacy |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Antimicrobial activity
- Coumarin
- Coumarin derivatives
ASJC Scopus subject areas
- Pharmaceutical Science
Cite this
Coumarins : The antimicrobial agents. / Al-Majedy, Yasameen K.; Kadhum, Abdul Amir H.; Al-Amiery, Ahmed A.; Mohamad, Abu Bakar.
In: Systematic Reviews in Pharmacy, Vol. 8, No. 1, 2016, p. 62-70.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Coumarins
T2 - The antimicrobial agents
AU - Al-Majedy, Yasameen K.
AU - Kadhum, Abdul Amir H.
AU - Al-Amiery, Ahmed A.
AU - Mohamad, Abu Bakar
PY - 2016
Y1 - 2016
N2 - Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because of their diverse biological activity and clinical applications, they are remarkably effective compounds both with respect to their inhibitory activity and their favourable selectivity ratio. Coumarins are regarded as a promising class of bioactive heterocyclic compounds that exhibit a range of biological activities like anti-microbial, anti-viral, anti-diabetic, anti-cancer activity, anti-oxidant, anti-parasitic, anti-helmintic, anti-proliferative, anti-convulsant, anti-inflammatory and anti-hypertensive activities etc. The information given in this manuscript may be helpful in the further research of better antimicrobial agents having lesser microbial resistance and improved antimicrobial profile.
AB - Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because of their diverse biological activity and clinical applications, they are remarkably effective compounds both with respect to their inhibitory activity and their favourable selectivity ratio. Coumarins are regarded as a promising class of bioactive heterocyclic compounds that exhibit a range of biological activities like anti-microbial, anti-viral, anti-diabetic, anti-cancer activity, anti-oxidant, anti-parasitic, anti-helmintic, anti-proliferative, anti-convulsant, anti-inflammatory and anti-hypertensive activities etc. The information given in this manuscript may be helpful in the further research of better antimicrobial agents having lesser microbial resistance and improved antimicrobial profile.
KW - Antimicrobial activity
KW - Coumarin
KW - Coumarin derivatives
UR - http://www.scopus.com/inward/record.url?scp=85018187004&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018187004&partnerID=8YFLogxK
U2 - 10.5530/srp.2017.1.11
DO - 10.5530/srp.2017.1.11
M3 - Review article
VL - 8
SP - 62
EP - 70
JO - Systematic Reviews in Pharmacy
JF - Systematic Reviews in Pharmacy
SN - 0975-8453
IS - 1
ER -