Consideration of nonuniformity in elongation of microstructures in a mechanically tunable microfluidic device for size-based isolation of microparticles

Jafar Alvankarian, Najmeh Sadat Jaddi, Mohammadmahdi Vakilian, Fatemeh Barantalab, A. Rahman A. Jamal, Burhanuddin Yeop Majlis

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This paper presents an investigation of the nonlinearity behavior in deformation that appears during the linear stretching of the elastomeric microstructures in a pillar-based microfilter. Determining the impact of the nonuniformity in strain on the geometry and performance of such a planar device under in-plane stretch is the motivation for this study. A semiempirical model is used to explain the physical strain-stress behavior from the root to the tip of the micropillars in the linear arrays in the device. For microfabrication of the device, the main substrate is elastomeric polyurethane methacrylate, which is utilized in an ultraviolet-molding method. Optical imaging and scanning electron microscopy were used to evaluate the deformation of the microstructures under different loading conditions. It was demonstrated that by applying mechanical strains of <20% ( Δ L/Lo) on the elastomeric device using a modified syringe pump, the spacing of the pillars is increased effectively to about three times the size of the initial setting of 5.5 μm, which corresponds to a strain of above 180% in the absence of nonuniformity effects. This simple yet interesting behavior can be exploited to rapidly adjust a microfluidic device for application to the separation of microbeads or blood cells, which would normally require the geometrical redesign and fabrication of a new device. [2014-0213]

Original languageEnglish
Article number6995983
Pages (from-to)309-318
Number of pages10
JournalJournal of Microelectromechanical Systems
Volume24
Issue number2
DOIs
Publication statusPublished - 1 Apr 2015

Fingerprint

Microfluidics
Elongation
Microstructure
Syringes
Microfabrication
Molding
Polyurethanes
Stretching
Blood
Cells
Pumps
Imaging techniques
Fabrication
Scanning electron microscopy
Geometry
Substrates

Keywords

  • elastomeric device
  • microfluidic rapid adjustment.
  • Non-uniform strain
  • pillar-based microfilter

ASJC Scopus subject areas

  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Consideration of nonuniformity in elongation of microstructures in a mechanically tunable microfluidic device for size-based isolation of microparticles. / Alvankarian, Jafar; Jaddi, Najmeh Sadat; Vakilian, Mohammadmahdi; Barantalab, Fatemeh; A. Jamal, A. Rahman; Yeop Majlis, Burhanuddin.

In: Journal of Microelectromechanical Systems, Vol. 24, No. 2, 6995983, 01.04.2015, p. 309-318.

Research output: Contribution to journalArticle

@article{9f20f1ebfc0b4b5ca5ce4adb295dd509,
title = "Consideration of nonuniformity in elongation of microstructures in a mechanically tunable microfluidic device for size-based isolation of microparticles",
abstract = "This paper presents an investigation of the nonlinearity behavior in deformation that appears during the linear stretching of the elastomeric microstructures in a pillar-based microfilter. Determining the impact of the nonuniformity in strain on the geometry and performance of such a planar device under in-plane stretch is the motivation for this study. A semiempirical model is used to explain the physical strain-stress behavior from the root to the tip of the micropillars in the linear arrays in the device. For microfabrication of the device, the main substrate is elastomeric polyurethane methacrylate, which is utilized in an ultraviolet-molding method. Optical imaging and scanning electron microscopy were used to evaluate the deformation of the microstructures under different loading conditions. It was demonstrated that by applying mechanical strains of <20{\%} ( Δ L/Lo) on the elastomeric device using a modified syringe pump, the spacing of the pillars is increased effectively to about three times the size of the initial setting of 5.5 μm, which corresponds to a strain of above 180{\%} in the absence of nonuniformity effects. This simple yet interesting behavior can be exploited to rapidly adjust a microfluidic device for application to the separation of microbeads or blood cells, which would normally require the geometrical redesign and fabrication of a new device. [2014-0213]",
keywords = "elastomeric device, microfluidic rapid adjustment., Non-uniform strain, pillar-based microfilter",
author = "Jafar Alvankarian and Jaddi, {Najmeh Sadat} and Mohammadmahdi Vakilian and Fatemeh Barantalab and {A. Jamal}, {A. Rahman} and {Yeop Majlis}, Burhanuddin",
year = "2015",
month = "4",
day = "1",
doi = "10.1109/JMEMS.2014.2378314",
language = "English",
volume = "24",
pages = "309--318",
journal = "Journal of Microelectromechanical Systems",
issn = "1057-7157",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "2",

}

TY - JOUR

T1 - Consideration of nonuniformity in elongation of microstructures in a mechanically tunable microfluidic device for size-based isolation of microparticles

AU - Alvankarian, Jafar

AU - Jaddi, Najmeh Sadat

AU - Vakilian, Mohammadmahdi

AU - Barantalab, Fatemeh

AU - A. Jamal, A. Rahman

AU - Yeop Majlis, Burhanuddin

PY - 2015/4/1

Y1 - 2015/4/1

N2 - This paper presents an investigation of the nonlinearity behavior in deformation that appears during the linear stretching of the elastomeric microstructures in a pillar-based microfilter. Determining the impact of the nonuniformity in strain on the geometry and performance of such a planar device under in-plane stretch is the motivation for this study. A semiempirical model is used to explain the physical strain-stress behavior from the root to the tip of the micropillars in the linear arrays in the device. For microfabrication of the device, the main substrate is elastomeric polyurethane methacrylate, which is utilized in an ultraviolet-molding method. Optical imaging and scanning electron microscopy were used to evaluate the deformation of the microstructures under different loading conditions. It was demonstrated that by applying mechanical strains of <20% ( Δ L/Lo) on the elastomeric device using a modified syringe pump, the spacing of the pillars is increased effectively to about three times the size of the initial setting of 5.5 μm, which corresponds to a strain of above 180% in the absence of nonuniformity effects. This simple yet interesting behavior can be exploited to rapidly adjust a microfluidic device for application to the separation of microbeads or blood cells, which would normally require the geometrical redesign and fabrication of a new device. [2014-0213]

AB - This paper presents an investigation of the nonlinearity behavior in deformation that appears during the linear stretching of the elastomeric microstructures in a pillar-based microfilter. Determining the impact of the nonuniformity in strain on the geometry and performance of such a planar device under in-plane stretch is the motivation for this study. A semiempirical model is used to explain the physical strain-stress behavior from the root to the tip of the micropillars in the linear arrays in the device. For microfabrication of the device, the main substrate is elastomeric polyurethane methacrylate, which is utilized in an ultraviolet-molding method. Optical imaging and scanning electron microscopy were used to evaluate the deformation of the microstructures under different loading conditions. It was demonstrated that by applying mechanical strains of <20% ( Δ L/Lo) on the elastomeric device using a modified syringe pump, the spacing of the pillars is increased effectively to about three times the size of the initial setting of 5.5 μm, which corresponds to a strain of above 180% in the absence of nonuniformity effects. This simple yet interesting behavior can be exploited to rapidly adjust a microfluidic device for application to the separation of microbeads or blood cells, which would normally require the geometrical redesign and fabrication of a new device. [2014-0213]

KW - elastomeric device

KW - microfluidic rapid adjustment.

KW - Non-uniform strain

KW - pillar-based microfilter

UR - http://www.scopus.com/inward/record.url?scp=85027934962&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85027934962&partnerID=8YFLogxK

U2 - 10.1109/JMEMS.2014.2378314

DO - 10.1109/JMEMS.2014.2378314

M3 - Article

AN - SCOPUS:85027934962

VL - 24

SP - 309

EP - 318

JO - Journal of Microelectromechanical Systems

JF - Journal of Microelectromechanical Systems

SN - 1057-7157

IS - 2

M1 - 6995983

ER -