Computational discovery of small open reading frames in Bacillus lehensis

Nurhafizhoh Zainuddin, Rosli Md Illias, Nor Muhammad Mahadi, Mohd Firdaus Mohd Raih

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Bacillus lehensis is a Gram-positive and endospore-forming alkalitolerant bacterial strain. In recent years there has been increasing interest in alkaliphilic bacteria and their ability to grow under extreme conditions as well as their ability to serve various important functions in industrial biology especially enzyme production. Small open reading frames (sORFs) have emerged as important regulators in various biological roles such as tumor progression, hormone signalling and stress response. Over the past decade, many biocomputational tools have been developed to predict genes in bacterial genomes. In this study, three softwares were used to predict sORF (≤ 80 aa) in B. lehensis by using whole genome sequence. We used comparative analysis to identify the sORFs in B. lehensis that conserved across all other bacterial genomes. We extended the analysis by doing the homology analysis against protein database. This study established the sORFs in B. lehensis that are conserved across bacteria which might has important biological function which still remain elusive in biological field.

Original languageEnglish
Title of host publication2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1678
ISBN (Electronic)9780735413252
DOIs
Publication statusPublished - 25 Sep 2015
Event2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015 - Selangor, Malaysia
Duration: 15 Apr 201516 Apr 2015

Other

Other2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015
CountryMalaysia
CitySelangor
Period15/4/1516/4/15

Fingerprint

Bacillus
genome
bacteria
hormones
regulators
homology
biology
progressions
genes
enzymes
tumors
proteins
computer programs

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Zainuddin, N., Illias, R. M., Mahadi, N. M., & Mohd Raih, M. F. (2015). Computational discovery of small open reading frames in Bacillus lehensis. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium (Vol. 1678). [030029] American Institute of Physics Inc.. https://doi.org/10.1063/1.4931250

Computational discovery of small open reading frames in Bacillus lehensis. / Zainuddin, Nurhafizhoh; Illias, Rosli Md; Mahadi, Nor Muhammad; Mohd Raih, Mohd Firdaus.

2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015. 030029.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zainuddin, N, Illias, RM, Mahadi, NM & Mohd Raih, MF 2015, Computational discovery of small open reading frames in Bacillus lehensis. in 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. vol. 1678, 030029, American Institute of Physics Inc., 2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015, Selangor, Malaysia, 15/4/15. https://doi.org/10.1063/1.4931250
Zainuddin N, Illias RM, Mahadi NM, Mohd Raih MF. Computational discovery of small open reading frames in Bacillus lehensis. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678. American Institute of Physics Inc. 2015. 030029 https://doi.org/10.1063/1.4931250
Zainuddin, Nurhafizhoh ; Illias, Rosli Md ; Mahadi, Nor Muhammad ; Mohd Raih, Mohd Firdaus. / Computational discovery of small open reading frames in Bacillus lehensis. 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015.
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