Comparison of stroke infarction between CT perfusion and diffusion weighted imaging -preliminary results

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper we present preliminary results of comparison of automatic segmentations of the infarct core, between that obtained from CT perfusion (based on time to peak parameter) and diffusion weighted imaging (DWI). For each patient, the two imaging volumes were automatically co-registered to a common frame of reference based on an acquired CT angiography image. The accuracy of image registration is measured by the overlap of the segmented brain from both images (CT perfusion and DWI), measured within their common field of view. Due to the limitations of the study, DWI was acquired as a follow up scan up to a week after initial CT based imaging. However, we found significant overlap of the segmented brain (Jaccard indices of approximately 0.8) and the percentage of infarcted brain tissue from the two modalities were still fairly highly correlated (correlation coefficient of approximately 0.9). The results are promising with more data needed in future for clinical inference.

Original languageEnglish
Title of host publicationMedical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
PublisherSPIE
Volume9788
ISBN (Electronic)9781510600232
DOIs
Publication statusPublished - 2016
EventMedical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging - San Diego, United States
Duration: 1 Mar 20163 Mar 2016

Other

OtherMedical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
CountryUnited States
CitySan Diego
Period1/3/163/3/16

Fingerprint

infarction
strokes
Infarction
Perfusion
Stroke
Imaging techniques
Brain
brain
Angiography
angiography
Image registration
inference
correlation coefficients
field of view
Tissue

Keywords

  • Comparison
  • CT perfusion
  • Diffusion weighted imaging
  • Image fusion
  • Image registration
  • Infarction
  • Multimodality
  • Stroke

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Abd Rahni, A. A., Arka, I. H., Chell, K., Mohamed Mukari, S. A., Law, Z. K., & Sahathevan, R. (2016). Comparison of stroke infarction between CT perfusion and diffusion weighted imaging -preliminary results. In Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging (Vol. 9788). [978824] SPIE. https://doi.org/10.1117/12.2218313

Comparison of stroke infarction between CT perfusion and diffusion weighted imaging -preliminary results. / Abd Rahni, Ashrani Aizzuddin; Arka, Israna Hossain; Chell, Kalaivani; Mohamed Mukari, Shahizon Azura; Law, Zhe Kang; Sahathevan, Ramesh.

Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 9788 SPIE, 2016. 978824.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abd Rahni, AA, Arka, IH, Chell, K, Mohamed Mukari, SA, Law, ZK & Sahathevan, R 2016, Comparison of stroke infarction between CT perfusion and diffusion weighted imaging -preliminary results. in Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. vol. 9788, 978824, SPIE, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, San Diego, United States, 1/3/16. https://doi.org/10.1117/12.2218313
Abd Rahni AA, Arka IH, Chell K, Mohamed Mukari SA, Law ZK, Sahathevan R. Comparison of stroke infarction between CT perfusion and diffusion weighted imaging -preliminary results. In Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 9788. SPIE. 2016. 978824 https://doi.org/10.1117/12.2218313
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