Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue

S. Ghanthimathi, Aminah Abdullah, S. Salmijah, T. Ujang, A. Nurul Izzah

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Fish is one of the most important sources of arsenic exposure in human diet and the Food Safety and Quality Division, Ministry of Health since 2007 has required routine monitoring of total arsenic in seafoods such as fish. This study describes an improved extraction method of total arsenic in fish using microwave assisted acid digestion procedure before being analysed by inductively coupled plasma mass spectrometry (ICP-MS). The parameters studied were pre-treatment of sample, digestion temperature, time programme and the chemicals (HNO3/H2O2) used. Arsenic contents in fish samples under these conditions were compared using the standards additions technique. Microwave assisted acid digestion method with a combination of ultrapure concentrated nitric acid (HNO3) to concentrated hydrogen peroxide (H2O2) at a ratio of 7 mL: 1 mL, run time of 25 min and digestion temperature of 200°C with no pre-treatment was found to have recovery of 100.7% as compared with other digestion procedure where the recovery were 115.5, 111.6 and 101.8%. Validation using certified reference material (CRM) of fish tissue (DORM-3) showed a recovery of 101.4 ± 2.5% for total arsenic from the CRM.

Original languageEnglish
Pages (from-to)1557-1564
Number of pages8
JournalSains Malaysiana
Volume41
Issue number12
Publication statusPublished - Dec 2012

Fingerprint

Inductively coupled plasma mass spectrometry
Arsenic
Fish
Microwaves
Tissue
Acids
Recovery
Nitric Acid
Food safety
Nutrition
Hydrogen Peroxide
Health
Temperature
Monitoring

Keywords

  • Arsenic
  • Certified reference material
  • Fish
  • Inductively coupled plasma mass spectrometry
  • Microwave assisted acid digestion

ASJC Scopus subject areas

  • General

Cite this

Ghanthimathi, S., Abdullah, A., Salmijah, S., Ujang, T., & Nurul Izzah, A. (2012). Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue. Sains Malaysiana, 41(12), 1557-1564.

Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue. / Ghanthimathi, S.; Abdullah, Aminah; Salmijah, S.; Ujang, T.; Nurul Izzah, A.

In: Sains Malaysiana, Vol. 41, No. 12, 12.2012, p. 1557-1564.

Research output: Contribution to journalArticle

Ghanthimathi, S, Abdullah, A, Salmijah, S, Ujang, T & Nurul Izzah, A 2012, 'Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue', Sains Malaysiana, vol. 41, no. 12, pp. 1557-1564.
Ghanthimathi S, Abdullah A, Salmijah S, Ujang T, Nurul Izzah A. Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue. Sains Malaysiana. 2012 Dec;41(12):1557-1564.
Ghanthimathi, S. ; Abdullah, Aminah ; Salmijah, S. ; Ujang, T. ; Nurul Izzah, A. / Comparison of microwave assisted acid digestion methods for ICP-MS determination of total arsenic in fish tissue. In: Sains Malaysiana. 2012 ; Vol. 41, No. 12. pp. 1557-1564.
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