Comparison between endonasal endoscopic polyp size scores and quality of life outcome after optimal medical treatment

Saleh Khaled Aboud, Salina Husain, Balwant Singh Gendeh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: The aim of this prospective study is to evaluate whether changes in endoscopy score correlate with changes in quality of life (QOL) in nasal polyposis (NP) patients after optimal medical therapy.

Methodology: An interventional clinical trial study involving fifty five patients with grade I and II NP was conducted. Patients were initially treated with a single dose oral prednisolone 25 mg for 2 weeks, Macrolide 250 mg daily for the first 3 months and long-term intranasal steroids. All patients were followed up and evaluated subjectively by Rhinosinusitis Disability Index questionnaire and objectively by endonasal endoscopy between December 2011 to October 2013.

Results: At baseline, patients showed significantly bad QOL scores on all domains. At 3 months, a significant improvement in all impaired QOL domains and reduction of the nasal polyp size were demonstrated compared to baseline. At 6 and 12 months, no significant improvement between QOL scores and nasal polyp size was observed.

Conclusion: Optimal medical treatments improve both the QOL and nasal polyp size in grade I and II NP patients. However, the changes in endoscopy scores explain a part of the improvement in QOL outcomes as the latter are multidimensional constructs.

Original languageEnglish
Pages (from-to)334-340
Number of pages7
JournalRhinology
Volume52
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Polyps
Quality of Life
Nasal Polyps
Nose
Endoscopy
Therapeutics
Macrolides
Prednisolone
Steroids
Clinical Trials
Prospective Studies

Keywords

  • Endonasal endoscopy
  • Medical polypectomy
  • Nasal polyposis
  • Quality of life

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Comparison between endonasal endoscopic polyp size scores and quality of life outcome after optimal medical treatment. / Aboud, Saleh Khaled; Husain, Salina; Gendeh, Balwant Singh.

In: Rhinology, Vol. 52, No. 4, 2014, p. 334-340.

Research output: Contribution to journalArticle

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