Comparison between effects of ketamine and midazolam as co-induction agents with propofol for proseal™ laryngeal mask insertion

Rafizah Latif Mohamad, Tang Suet Ping Shereen, Nurlia Yahya, Azarinah Izaham, Aliza Mohamad Yusof, Norsidah Abdul Manap

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction: Optimal conditions during supraglottic airway placement are important to prevent adverse events associated with inadequate depth of anaesthesia. This study compared propofol co-induction with ketamine or midazolam during ProSeal™ Laryngeal Mask Airway (PLMA) insertion. Materials and Methods: A total of 118 ASA I or II patients aged between 18 to 60 years requiring PLMA insertion for surgery were recruited into this prospective, randomised and double blind study. Patients were grouped into propofol (2mg/kg) co-induction with either ketamine (0.5mg/kg) or midazolam (0.03mg/kg). During PLMA insertion, the degree of mouth opening, ease of insertion, swallowing, coughing or gagging, movement and laryngospasm were scored and haemodynamic changes were recorded. Overall insertion conditions were further graded into excellent, good, poor or unacceptable. Results: The ketamine-propofol group had significantly better mouth opening (p=0.01) and shorter duration of apnoea (p

Original languageEnglish
Pages (from-to)16-21
Number of pages6
JournalSri Lankan Journal of Anaesthesiology
Volume24
Issue number1
DOIs
Publication statusPublished - 2016

Fingerprint

Laryngeal Masks
Midazolam
Ketamine
Propofol
Mouth
Gagging
Laryngismus
Apnea
Deglutition
Double-Blind Method
Anesthesia
Hemodynamics

Keywords

  • Co-induction
  • Ketamine
  • Midazolam
  • Propofol
  • Proseal™ laryngeal mask insertion

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Comparison between effects of ketamine and midazolam as co-induction agents with propofol for proseal™ laryngeal mask insertion. / Mohamad, Rafizah Latif; Shereen, Tang Suet Ping; Yahya, Nurlia; Izaham, Azarinah; Yusof, Aliza Mohamad; Abdul Manap, Norsidah.

In: Sri Lankan Journal of Anaesthesiology, Vol. 24, No. 1, 2016, p. 16-21.

Research output: Contribution to journalArticle

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