Comparing intrinsic connectivity models for the primary auditory cortices

Khairiah Abdul Hamid, Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Aini Ismafairus Abd Hamid, Hanani Abd Manan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This fMRI study is about modeling the intrinsic connectivity between Heschl' gyrus (HG) and superior temporal gyrus (STG) in human primary auditory cortices. Ten healthy male subjects participated and required to listen to white noise stimulus during the fMRI scans. Two intrinsic connectivity models comprising bilateral HG and STG were constructed using statistical parametric mapping (SPM) and dynamic causal modeling (DCM). Group Bayes factor (GBF), positive evidence ratio (PER) and Bayesian model selection (BMS) for group studies were used in model comparison. Group results indicated significant bilateral asymmetrical activation (puncorr<0.001) in HG and STG. Comparison results showed strong evidence of Model 2 as the preferred model (STG as the input center) with GBF value of 5.77×1073 The model is preferred by 6 out of 10 subjects. The results were supported by BMS results for group studies. One-sample t-test on connection values obtained from Model 2 indicates unidirectional parallel connections from STG to bilateral HG (p<0.05). Model 2 was determined to be the most probable intrinsic connectivity model between bilateral HG and STG when listening to white noise.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages389-392
Number of pages4
Volume1250
DOIs
Publication statusPublished - 2010
EventProgress of Physics Research in Malaysia, PERFIK2009 - Malacca
Duration: 7 Dec 20099 Dec 2009

Other

OtherProgress of Physics Research in Malaysia, PERFIK2009
CityMalacca
Period7/12/099/12/09

Fingerprint

cortexes
white noise
stimuli
activation

Keywords

  • Bayes factor
  • Bayesian model selection
  • Dynamic causal modeling
  • fMRI
  • SPM

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Hamid, K. A., Yusoff, A. N., Mohamad, M., Hamid, A. I. A., & Manan, H. A. (2010). Comparing intrinsic connectivity models for the primary auditory cortices. In AIP Conference Proceedings (Vol. 1250, pp. 389-392) https://doi.org/10.1063/1.3469687

Comparing intrinsic connectivity models for the primary auditory cortices. / Hamid, Khairiah Abdul; Yusoff, Ahmad Nazlim; Mohamad, Mazlyfarina; Hamid, Aini Ismafairus Abd; Manan, Hanani Abd.

AIP Conference Proceedings. Vol. 1250 2010. p. 389-392.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hamid, KA, Yusoff, AN, Mohamad, M, Hamid, AIA & Manan, HA 2010, Comparing intrinsic connectivity models for the primary auditory cortices. in AIP Conference Proceedings. vol. 1250, pp. 389-392, Progress of Physics Research in Malaysia, PERFIK2009, Malacca, 7/12/09. https://doi.org/10.1063/1.3469687
Hamid KA, Yusoff AN, Mohamad M, Hamid AIA, Manan HA. Comparing intrinsic connectivity models for the primary auditory cortices. In AIP Conference Proceedings. Vol. 1250. 2010. p. 389-392 https://doi.org/10.1063/1.3469687
Hamid, Khairiah Abdul ; Yusoff, Ahmad Nazlim ; Mohamad, Mazlyfarina ; Hamid, Aini Ismafairus Abd ; Manan, Hanani Abd. / Comparing intrinsic connectivity models for the primary auditory cortices. AIP Conference Proceedings. Vol. 1250 2010. pp. 389-392
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