Combination of Er: YAG laser and CO2 laser treatment on skin Tissue

Sana Mohammed Anayb Baleg, Noriah Bidin, Lau Pik Suan, Muhammad Fakarruddin Sidi Ahmad, Ganesan Krishnan, Abd Rahman Johari, Asmah Hamid

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Skin is the most important organ in our body, as it protects us from external environmental effects. Study the ability of the skin to stretch and the histological examinations of irradiated tissues have significant values in scientific and medical applications. Only a few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed with dual lasers in an in vivo rat model. All laser exposures led to mark improvement in the skin's strength compared to their own controls. The histological investigation indicated that there was a thickness loss in the epidermis layer with the induction of deep collagen coagulation in the dermis layer as the dual laser pulses increased. Additionally, more collagen fibers were remolded in the treated samples by dual wavelengths. We conclude that by combining dual lasers with multiple pulses targeted at not only the epidermis layer of the skin, it could also induce some heat diffusion in the dermis layer which causes more coagulation of collagen fibers. The tensile results confirmed by our histological data demonstrate that the strength of irradiated skin with dual wavelengths increased more than using both lasers separately on the skin tissue since more collagen is induced. The skin is an important body-organ, protecting us from external environmental effects. Studies concerning the ability of skin to stretch and histological examinations of irradiated tissues have significant values for scientific and medical applications. Only few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed to dual lasers in an in vivo rat model.

Original languageEnglish
Pages (from-to)134-138
Number of pages5
JournalPhotochemistry and Photobiology
Volume91
Issue number1
DOIs
Publication statusPublished - 2015

Fingerprint

Gas Lasers
Solid-State Lasers
YAG lasers
Skin
collagens
Tissue
epidermis
Lasers
Collagen
lasers
Epidermis
coagulation
pulses
organs
ablation
rats
Medical applications
Laser modes
Ablation
Coagulation

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Biochemistry
  • Medicine(all)

Cite this

Anayb Baleg, S. M., Bidin, N., Suan, L. P., Sidi Ahmad, M. F., Krishnan, G., Johari, A. R., & Hamid, A. (2015). Combination of Er: YAG laser and CO2 laser treatment on skin Tissue. Photochemistry and Photobiology, 91(1), 134-138. https://doi.org/10.1111/php.12369

Combination of Er : YAG laser and CO2 laser treatment on skin Tissue. / Anayb Baleg, Sana Mohammed; Bidin, Noriah; Suan, Lau Pik; Sidi Ahmad, Muhammad Fakarruddin; Krishnan, Ganesan; Johari, Abd Rahman; Hamid, Asmah.

In: Photochemistry and Photobiology, Vol. 91, No. 1, 2015, p. 134-138.

Research output: Contribution to journalArticle

Anayb Baleg, SM, Bidin, N, Suan, LP, Sidi Ahmad, MF, Krishnan, G, Johari, AR & Hamid, A 2015, 'Combination of Er: YAG laser and CO2 laser treatment on skin Tissue', Photochemistry and Photobiology, vol. 91, no. 1, pp. 134-138. https://doi.org/10.1111/php.12369
Anayb Baleg SM, Bidin N, Suan LP, Sidi Ahmad MF, Krishnan G, Johari AR et al. Combination of Er: YAG laser and CO2 laser treatment on skin Tissue. Photochemistry and Photobiology. 2015;91(1):134-138. https://doi.org/10.1111/php.12369
Anayb Baleg, Sana Mohammed ; Bidin, Noriah ; Suan, Lau Pik ; Sidi Ahmad, Muhammad Fakarruddin ; Krishnan, Ganesan ; Johari, Abd Rahman ; Hamid, Asmah. / Combination of Er : YAG laser and CO2 laser treatment on skin Tissue. In: Photochemistry and Photobiology. 2015 ; Vol. 91, No. 1. pp. 134-138.
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