Cohort Profile

The Malaysian Cohort (TMC) project: A prospective study of non-communicable diseases in a multi-ethnic population

Malaysian Cohort Study Group

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The Malaysian Cohort study was initiated in 2005 by the Malaysian government. The top-down approach to this population-based cohort study ensured the allocation of sufficient funding for the project which aimed to recruit 100 000 individuals aged 35-70 years. Participants were recruited from rural and urban areas as well as from various socioeconomic groups. The main objectives of the study were to identify risk factors, to study gene-environment interaction and to discover biomarkers for the early detection of cancers and other diseases. At recruitment, a questionnaire-based interview was conducted, biophysical measurements were performed and biospecimens were collected, processed and stored. Baseline investigations included fasting blood sugar, fasting lipid profile, renal profile and full blood count. From April 2006 to the end of September 2012 we recruited a total of 106 527participants. The baseline prevalence data showed 16.6% participants with diabetes, 46.5% with hypertension, 44.9% with hypercholesterolaemia and 17.7% with obesity. The follow-up phase commenced in June 2013. This is the most comprehensive and biggest cohort study in Malaysia, and has become a valuable resource for epidemiological and biological research. For information on collaboration and also data access, investigators can contact the project leader at (rahmanj@ppukm.ukm.edu.my).

Original languageEnglish
Article numberdyu089
Pages (from-to)423-431
Number of pages9
JournalInternational Journal of Epidemiology
Volume44
Issue number2
DOIs
Publication statusPublished - 27 May 2015

Fingerprint

Cohort Studies
Prospective Studies
Fasting
Population
Gene-Environment Interaction
Malaysia
Hypercholesterolemia
Early Detection of Cancer
Blood Glucose
Obesity
Biomarkers
Research Personnel
Interviews
Hypertension
Kidney
Lipids
Research
Surveys and Questionnaires

ASJC Scopus subject areas

  • Epidemiology

Cite this

Cohort Profile : The Malaysian Cohort (TMC) project: A prospective study of non-communicable diseases in a multi-ethnic population. / Malaysian Cohort Study Group.

In: International Journal of Epidemiology, Vol. 44, No. 2, dyu089, 27.05.2015, p. 423-431.

Research output: Contribution to journalArticle

@article{0521bd7c97c1454e89547fafe582c507,
title = "Cohort Profile: The Malaysian Cohort (TMC) project: A prospective study of non-communicable diseases in a multi-ethnic population",
abstract = "The Malaysian Cohort study was initiated in 2005 by the Malaysian government. The top-down approach to this population-based cohort study ensured the allocation of sufficient funding for the project which aimed to recruit 100 000 individuals aged 35-70 years. Participants were recruited from rural and urban areas as well as from various socioeconomic groups. The main objectives of the study were to identify risk factors, to study gene-environment interaction and to discover biomarkers for the early detection of cancers and other diseases. At recruitment, a questionnaire-based interview was conducted, biophysical measurements were performed and biospecimens were collected, processed and stored. Baseline investigations included fasting blood sugar, fasting lipid profile, renal profile and full blood count. From April 2006 to the end of September 2012 we recruited a total of 106 527participants. The baseline prevalence data showed 16.6{\%} participants with diabetes, 46.5{\%} with hypertension, 44.9{\%} with hypercholesterolaemia and 17.7{\%} with obesity. The follow-up phase commenced in June 2013. This is the most comprehensive and biggest cohort study in Malaysia, and has become a valuable resource for epidemiological and biological research. For information on collaboration and also data access, investigators can contact the project leader at (rahmanj@ppukm.ukm.edu.my).",
author = "{Malaysian Cohort Study Group} and {A. Jamal}, {A. Rahman} and {Syed Zakaria}, {Syed Zulkifli} and Kamaruddin, {Mohd Arman} and {Abd Jalal}, Nazihah and Norliza Ismail and {Mohd Kamil}, Norkhamiwati and {Abdullah @ Muda}, Noraidatulakma and Norhafizah Baharudin and Hussin, {Noor Hamidah} and Hanita Othman and Mahadi, {Nor Muhammad} and {Abd Rahman}, {Abd Rashid} and Afifah Awang and Jamil, {Ahmad Taufik} and Mustafa, {Amal Nasir} and Nuruddin, {Amin Ariff} and Amin Ismail and {Abd Hamid Karim}, Aminuddin and Nur, {Amrizal Muhd} and Andri Dauni and Sallam, {Atiya Ab} and Christopher Lee and Deepak Rebentisch and Chye, {Lim Chin} and Anshar, {Fauzi Md} and Ghufran Ridzuan and Hashami Bohari and Hayati Aziz and Rahman, {Hejar Abdul} and Ismail, {Ikram Shah} and Ismail Noor and Jamaiyah Haniff and Hashim, {Jamal Hisham} and Rahman, {Jamalludin Ab} and Khadijah Shamsuddin and Rampal, {Krishna Gopal} and Sulaiman, {Lokman Hakim} and Mirnalini Kandiah and {Mohd Hashim}, {Mohamad Ariff} and Omar, {Mohd Hashim} and Isa, {Mohd Nizam} and {Abdul Manaf}, {Mohd Rizal} and Kamaluddin, {Muhammad Amir} and Kamaruddin, {Nor Azmi} and {A. Karim}, Norimah and Poh, {Bee Koon} and Saperi Sulong and {Mohd Noah}, {Shahrul Azman} and Suzana Shahar and {Mohd Yusof}, {Yasmin Anum}",
year = "2015",
month = "5",
day = "27",
doi = "10.1093/ije/dyu089",
language = "English",
volume = "44",
pages = "423--431",
journal = "International Journal of Epidemiology",
issn = "0300-5771",
publisher = "Oxford University Press",
number = "2",

}

TY - JOUR

T1 - Cohort Profile

T2 - The Malaysian Cohort (TMC) project: A prospective study of non-communicable diseases in a multi-ethnic population

AU - Malaysian Cohort Study Group

AU - A. Jamal, A. Rahman

AU - Syed Zakaria, Syed Zulkifli

AU - Kamaruddin, Mohd Arman

AU - Abd Jalal, Nazihah

AU - Ismail, Norliza

AU - Mohd Kamil, Norkhamiwati

AU - Abdullah @ Muda, Noraidatulakma

AU - Baharudin, Norhafizah

AU - Hussin, Noor Hamidah

AU - Othman, Hanita

AU - Mahadi, Nor Muhammad

AU - Abd Rahman, Abd Rashid

AU - Awang, Afifah

AU - Jamil, Ahmad Taufik

AU - Mustafa, Amal Nasir

AU - Nuruddin, Amin Ariff

AU - Ismail, Amin

AU - Abd Hamid Karim, Aminuddin

AU - Nur, Amrizal Muhd

AU - Dauni, Andri

AU - Sallam, Atiya Ab

AU - Lee, Christopher

AU - Rebentisch, Deepak

AU - Chye, Lim Chin

AU - Anshar, Fauzi Md

AU - Ridzuan, Ghufran

AU - Bohari, Hashami

AU - Aziz, Hayati

AU - Rahman, Hejar Abdul

AU - Ismail, Ikram Shah

AU - Noor, Ismail

AU - Haniff, Jamaiyah

AU - Hashim, Jamal Hisham

AU - Rahman, Jamalludin Ab

AU - Shamsuddin, Khadijah

AU - Rampal, Krishna Gopal

AU - Sulaiman, Lokman Hakim

AU - Kandiah, Mirnalini

AU - Mohd Hashim, Mohamad Ariff

AU - Omar, Mohd Hashim

AU - Isa, Mohd Nizam

AU - Abdul Manaf, Mohd Rizal

AU - Kamaluddin, Muhammad Amir

AU - Kamaruddin, Nor Azmi

AU - A. Karim, Norimah

AU - Poh, Bee Koon

AU - Sulong, Saperi

AU - Mohd Noah, Shahrul Azman

AU - Shahar, Suzana

AU - Mohd Yusof, Yasmin Anum

PY - 2015/5/27

Y1 - 2015/5/27

N2 - The Malaysian Cohort study was initiated in 2005 by the Malaysian government. The top-down approach to this population-based cohort study ensured the allocation of sufficient funding for the project which aimed to recruit 100 000 individuals aged 35-70 years. Participants were recruited from rural and urban areas as well as from various socioeconomic groups. The main objectives of the study were to identify risk factors, to study gene-environment interaction and to discover biomarkers for the early detection of cancers and other diseases. At recruitment, a questionnaire-based interview was conducted, biophysical measurements were performed and biospecimens were collected, processed and stored. Baseline investigations included fasting blood sugar, fasting lipid profile, renal profile and full blood count. From April 2006 to the end of September 2012 we recruited a total of 106 527participants. The baseline prevalence data showed 16.6% participants with diabetes, 46.5% with hypertension, 44.9% with hypercholesterolaemia and 17.7% with obesity. The follow-up phase commenced in June 2013. This is the most comprehensive and biggest cohort study in Malaysia, and has become a valuable resource for epidemiological and biological research. For information on collaboration and also data access, investigators can contact the project leader at (rahmanj@ppukm.ukm.edu.my).

AB - The Malaysian Cohort study was initiated in 2005 by the Malaysian government. The top-down approach to this population-based cohort study ensured the allocation of sufficient funding for the project which aimed to recruit 100 000 individuals aged 35-70 years. Participants were recruited from rural and urban areas as well as from various socioeconomic groups. The main objectives of the study were to identify risk factors, to study gene-environment interaction and to discover biomarkers for the early detection of cancers and other diseases. At recruitment, a questionnaire-based interview was conducted, biophysical measurements were performed and biospecimens were collected, processed and stored. Baseline investigations included fasting blood sugar, fasting lipid profile, renal profile and full blood count. From April 2006 to the end of September 2012 we recruited a total of 106 527participants. The baseline prevalence data showed 16.6% participants with diabetes, 46.5% with hypertension, 44.9% with hypercholesterolaemia and 17.7% with obesity. The follow-up phase commenced in June 2013. This is the most comprehensive and biggest cohort study in Malaysia, and has become a valuable resource for epidemiological and biological research. For information on collaboration and also data access, investigators can contact the project leader at (rahmanj@ppukm.ukm.edu.my).

UR - http://www.scopus.com/inward/record.url?scp=84936769188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84936769188&partnerID=8YFLogxK

U2 - 10.1093/ije/dyu089

DO - 10.1093/ije/dyu089

M3 - Article

VL - 44

SP - 423

EP - 431

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

SN - 0300-5771

IS - 2

M1 - dyu089

ER -