CNS germinoma with extensive calcification

An unusual histologic finding

Geok Chin Tan, S. Sallapan, K. Haworth, J. Finlay, D. R. Boue, C. R. Pierson

Research output: Contribution to journalArticle

Abstract

INTRODUCTION: Intratumoral calcification is a feature that is more often observed in pineal parenchymal tumour than germinoma. We describe a 13-year-old male with pineal region germinoma demonstrating extensive intratumoral calcification. CASE REPORT: He presented with worsening headache that was associated with fatigue, nausea and vomiting. Radiologic examination revealed a multilobular mass in the pineal region with internal calcifications. Biopsy showed a pure germinoma with unusually extensive calcification. DISCUSSION: Although a diagnosis may be suggested with a careful evaluation of imaging, there is no pathognomonic pattern. Thus, histologic verification is necessary for most pineal region masses.

Original languageEnglish
Pages (from-to)71-73
Number of pages3
JournalThe Malaysian journal of pathology
Volume41
Issue number1
Publication statusPublished - 1 Apr 2019

Fingerprint

Germinoma
Pinealoma
Nausea
Vomiting
Fatigue
Headache
Biopsy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

Cite this

Tan, G. C., Sallapan, S., Haworth, K., Finlay, J., Boue, D. R., & Pierson, C. R. (2019). CNS germinoma with extensive calcification: An unusual histologic finding. The Malaysian journal of pathology, 41(1), 71-73.

CNS germinoma with extensive calcification : An unusual histologic finding. / Tan, Geok Chin; Sallapan, S.; Haworth, K.; Finlay, J.; Boue, D. R.; Pierson, C. R.

In: The Malaysian journal of pathology, Vol. 41, No. 1, 01.04.2019, p. 71-73.

Research output: Contribution to journalArticle

Tan, GC, Sallapan, S, Haworth, K, Finlay, J, Boue, DR & Pierson, CR 2019, 'CNS germinoma with extensive calcification: An unusual histologic finding', The Malaysian journal of pathology, vol. 41, no. 1, pp. 71-73.
Tan GC, Sallapan S, Haworth K, Finlay J, Boue DR, Pierson CR. CNS germinoma with extensive calcification: An unusual histologic finding. The Malaysian journal of pathology. 2019 Apr 1;41(1):71-73.
Tan, Geok Chin ; Sallapan, S. ; Haworth, K. ; Finlay, J. ; Boue, D. R. ; Pierson, C. R. / CNS germinoma with extensive calcification : An unusual histologic finding. In: The Malaysian journal of pathology. 2019 ; Vol. 41, No. 1. pp. 71-73.
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