Clinicopathological observations of clostridium perfringens toxins in experimental guineapigs

M. S. Rahman, Md. Mostafizur Rahman, M. A H N A Khan

Research output: Contribution to journalArticle

Abstract

Clsostridium perfrigens is an important pathogen a wide spectrum of human and veterinary causing diseases (McClane, 1992). It is considered to be the most widely occuring pathogenic bacterium (Hatheway, 1990) . The organism produces several toxins of which beta and epsilon are the most lethal (El-Idrissi and Ward, 1992). Pathological changes produced by whole growing culture of Clostridium perfringens in guineapigs has been reported (Tripathi et al. 1993b). Several authors (Lawrence and Walker, 1976; Lawrence and Cooke, 1980) failed to produce disease in guineapigs by filtrate of Clostridium perfringens orally which might be due to neutralization of toxin by pancreatic juice in duodenum. Therefore an attempt has been made to observe the clinical and pathological findings in guineapigs with intraperitoneal and intradermal administration of Clostridium perfringens toxins.

Original languageEnglish
Pages (from-to)497-500
Number of pages4
JournalIndian Veterinary Journal
Volume76
Issue number6
Publication statusPublished - 1999
Externally publishedYes

Fingerprint

Clostridium perfringens
guinea pigs
toxins
pancreatic juice
Pancreatic Juice
filtrates
duodenum
Duodenum
neutralization
Bacteria
pathogens
bacteria
organisms

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Rahman, M. S., Rahman, M. M., & Khan, M. A. H. N. A. (1999). Clinicopathological observations of clostridium perfringens toxins in experimental guineapigs. Indian Veterinary Journal, 76(6), 497-500.

Clinicopathological observations of clostridium perfringens toxins in experimental guineapigs. / Rahman, M. S.; Rahman, Md. Mostafizur; Khan, M. A H N A.

In: Indian Veterinary Journal, Vol. 76, No. 6, 1999, p. 497-500.

Research output: Contribution to journalArticle

Rahman, M. S. ; Rahman, Md. Mostafizur ; Khan, M. A H N A. / Clinicopathological observations of clostridium perfringens toxins in experimental guineapigs. In: Indian Veterinary Journal. 1999 ; Vol. 76, No. 6. pp. 497-500.
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