Clinical characteristics of keratoconus patients in Malaysia

A review from a cornea specialist centre

Bariah Mohd. Ali, Mustafa Abdu, Choong Yean Yaw, Norhani Mohidin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Purpose: To evaluate the demographic profile, refraction, visual acuity (VA), corneal curvature (K) and severity of keratoconus (KC) patients from a cornea specialist centre in Malaysia. This may improve the management of KC patients in this country. Methods: Records of 13,000 patients were reviewed. The patients were categorized into 4 age groups: (Gp 1: <23 years, Gp 2: 23-32 years, Gp 3: 33-42 years, Gp 4: >42 years). Refraction and VA were determined using subjective refraction and Snellen chart. Corneal curvature was measured using Orbscan II topography. Severity of KC was graded following Amsler-Krumeich system. Data were analysed according to age, gender and ethnicity. Results: A total of 159 patients had KC and the prevalence was 1.2%. Mean age of onset was 20.9 ± 5.6 years, with 71.1% of males and 28.9% of females. Majority were of Indian and Malay origins. Percentages of patients within each age group were 26.4%, 52.8%, 18.9% and 1.9% respectively. Regarding severity, 37.6% were stage I, 30.1% stage II, 4.4% stage III and 27.8% stage IV at the time of diagnosis. The age of onset, refraction, mean K and VA was found to be similar between gender and ethnicity (p > 0.05). Age of onset was not strongly correlated to the severity of the disease. Conclusion: This study concludes that there are higher percentages of Malays and Indians with KC than other races in Malaysia. The condition was found to manifest at a younger age and was more common in males than females. These findings should be considered during vision screening in Malaysia.

Original languageEnglish
Pages (from-to)38-42
Number of pages5
JournalJournal of Optometry
Volume5
Issue number1
DOIs
Publication statusPublished - Jan 2012

Fingerprint

Keratoconus
Malaysia
Cornea
Age of Onset
Visual Acuity
Age Groups
Vision Screening
Demography

Keywords

  • Age
  • Ethnicity
  • Gender
  • Keratoconus
  • Keratometer

ASJC Scopus subject areas

  • Optometry

Cite this

Clinical characteristics of keratoconus patients in Malaysia : A review from a cornea specialist centre. / Mohd. Ali, Bariah; Abdu, Mustafa; Yaw, Choong Yean; Mohidin, Norhani.

In: Journal of Optometry, Vol. 5, No. 1, 01.2012, p. 38-42.

Research output: Contribution to journalArticle

Mohd. Ali, Bariah ; Abdu, Mustafa ; Yaw, Choong Yean ; Mohidin, Norhani. / Clinical characteristics of keratoconus patients in Malaysia : A review from a cornea specialist centre. In: Journal of Optometry. 2012 ; Vol. 5, No. 1. pp. 38-42.
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abstract = "Purpose: To evaluate the demographic profile, refraction, visual acuity (VA), corneal curvature (K) and severity of keratoconus (KC) patients from a cornea specialist centre in Malaysia. This may improve the management of KC patients in this country. Methods: Records of 13,000 patients were reviewed. The patients were categorized into 4 age groups: (Gp 1: <23 years, Gp 2: 23-32 years, Gp 3: 33-42 years, Gp 4: >42 years). Refraction and VA were determined using subjective refraction and Snellen chart. Corneal curvature was measured using Orbscan II topography. Severity of KC was graded following Amsler-Krumeich system. Data were analysed according to age, gender and ethnicity. Results: A total of 159 patients had KC and the prevalence was 1.2{\%}. Mean age of onset was 20.9 ± 5.6 years, with 71.1{\%} of males and 28.9{\%} of females. Majority were of Indian and Malay origins. Percentages of patients within each age group were 26.4{\%}, 52.8{\%}, 18.9{\%} and 1.9{\%} respectively. Regarding severity, 37.6{\%} were stage I, 30.1{\%} stage II, 4.4{\%} stage III and 27.8{\%} stage IV at the time of diagnosis. The age of onset, refraction, mean K and VA was found to be similar between gender and ethnicity (p > 0.05). Age of onset was not strongly correlated to the severity of the disease. Conclusion: This study concludes that there are higher percentages of Malays and Indians with KC than other races in Malaysia. The condition was found to manifest at a younger age and was more common in males than females. These findings should be considered during vision screening in Malaysia.",
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