Clinical characteristics and treatment outcome of gastrointestinal non-Hodgkin's lymphoma

Praveen Singam, Chee Kong Christopher Ho, S Fadilah S. Abdul Wahid, Ismail Sagap

Research output: Contribution to journalArticle

Abstract

Primary gastrointestinal (GIT) lymphoma constitutes only 5 - 10% of all gastrointestinal tumours. The optimal therapy for these lymphomas is poorly defined and still controversial. We present our experience in the treatment and outcome of primary GIT lymphomas in UKM Medical Center, Malaysia. A retrospective review of all patients with primary GIT lymphoma from the year 2002 until 2007 was done. Our series has shown that primary GIT lymphoma is a rare disease as it comprises only 6.5% of all lymphomas treated in this institution. We had a female predominance of this disease with a large majority at an advanced stage of the disease. There was equal distribution involving stomach, small and large intestines. The incidence of primary GIT lymphomas was 6.5% with a female predominance. The majority had advanced diseases (stage III and IV) with equal distribution involving the stomach, small and large intestines. The most common histological variant was diffuse large B cell lymphoma (66%). Most (83%) patients with intestinal lymphoma had surgical resection and adjuvant chemotherapy. All patients with gastric lymphomas had chemotherapy alone. The mortality rate was 22% predominantly in younger patients with aggressive histology subtypes and advanced disease.

Original languageEnglish
Pages (from-to)98-100
Number of pages3
JournalMedical Journal of Malaysia
Volume65
Issue number2
Publication statusPublished - Jun 2010

Fingerprint

Non-Hodgkin's Lymphoma
Lymphoma
Large Intestine
Small Intestine
Stomach
Lymphoma, Large B-Cell, Diffuse
Malaysia
Adjuvant Chemotherapy
Rare Diseases
Histology
Drug Therapy
Mortality
Incidence
Neoplasms

Keywords

  • Extranodal lymphoma
  • Non-Hodgkin's lymphoma
  • Primary gastrointestinal lymphoma

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Clinical characteristics and treatment outcome of gastrointestinal non-Hodgkin's lymphoma. / Singam, Praveen; Ho, Chee Kong Christopher; S. Abdul Wahid, S Fadilah; Sagap, Ismail.

In: Medical Journal of Malaysia, Vol. 65, No. 2, 06.2010, p. 98-100.

Research output: Contribution to journalArticle

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