Abstract
Primary gastrointestinal (GIT) lymphoma constitutes only 5 - 10% of all gastrointestinal tumours. The optimal therapy for these lymphomas is poorly defined and still controversial. We present our experience in the treatment and outcome of primary GIT lymphomas in UKM Medical Center, Malaysia. A retrospective review of all patients with primary GIT lymphoma from the year 2002 until 2007 was done. Our series has shown that primary GIT lymphoma is a rare disease as it comprises only 6.5% of all lymphomas treated in this institution. We had a female predominance of this disease with a large majority at an advanced stage of the disease. There was equal distribution involving stomach, small and large intestines. The incidence of primary GIT lymphomas was 6.5% with a female predominance. The majority had advanced diseases (stage III and IV) with equal distribution involving the stomach, small and large intestines. The most common histological variant was diffuse large B cell lymphoma (66%). Most (83%) patients with intestinal lymphoma had surgical resection and adjuvant chemotherapy. All patients with gastric lymphomas had chemotherapy alone. The mortality rate was 22% predominantly in younger patients with aggressive histology subtypes and advanced disease.
| Original language | English |
|---|---|
| Pages (from-to) | 98-100 |
| Number of pages | 3 |
| Journal | Medical Journal of Malaysia |
| Volume | 65 |
| Issue number | 2 |
| Publication status | Published - Jun 2010 |
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Keywords
- Extranodal lymphoma
- Non-Hodgkin's lymphoma
- Primary gastrointestinal lymphoma
ASJC Scopus subject areas
- Medicine(all)
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Clinical characteristics and treatment outcome of gastrointestinal non-Hodgkin's lymphoma. / Singam, Praveen; Ho, Chee Kong Christopher; S. Abdul Wahid, S Fadilah; Sagap, Ismail.
In: Medical Journal of Malaysia, Vol. 65, No. 2, 06.2010, p. 98-100.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical characteristics and treatment outcome of gastrointestinal non-Hodgkin's lymphoma
AU - Singam, Praveen
AU - Ho, Chee Kong Christopher
AU - S. Abdul Wahid, S Fadilah
AU - Sagap, Ismail
PY - 2010/6
Y1 - 2010/6
N2 - Primary gastrointestinal (GIT) lymphoma constitutes only 5 - 10% of all gastrointestinal tumours. The optimal therapy for these lymphomas is poorly defined and still controversial. We present our experience in the treatment and outcome of primary GIT lymphomas in UKM Medical Center, Malaysia. A retrospective review of all patients with primary GIT lymphoma from the year 2002 until 2007 was done. Our series has shown that primary GIT lymphoma is a rare disease as it comprises only 6.5% of all lymphomas treated in this institution. We had a female predominance of this disease with a large majority at an advanced stage of the disease. There was equal distribution involving stomach, small and large intestines. The incidence of primary GIT lymphomas was 6.5% with a female predominance. The majority had advanced diseases (stage III and IV) with equal distribution involving the stomach, small and large intestines. The most common histological variant was diffuse large B cell lymphoma (66%). Most (83%) patients with intestinal lymphoma had surgical resection and adjuvant chemotherapy. All patients with gastric lymphomas had chemotherapy alone. The mortality rate was 22% predominantly in younger patients with aggressive histology subtypes and advanced disease.
AB - Primary gastrointestinal (GIT) lymphoma constitutes only 5 - 10% of all gastrointestinal tumours. The optimal therapy for these lymphomas is poorly defined and still controversial. We present our experience in the treatment and outcome of primary GIT lymphomas in UKM Medical Center, Malaysia. A retrospective review of all patients with primary GIT lymphoma from the year 2002 until 2007 was done. Our series has shown that primary GIT lymphoma is a rare disease as it comprises only 6.5% of all lymphomas treated in this institution. We had a female predominance of this disease with a large majority at an advanced stage of the disease. There was equal distribution involving stomach, small and large intestines. The incidence of primary GIT lymphomas was 6.5% with a female predominance. The majority had advanced diseases (stage III and IV) with equal distribution involving the stomach, small and large intestines. The most common histological variant was diffuse large B cell lymphoma (66%). Most (83%) patients with intestinal lymphoma had surgical resection and adjuvant chemotherapy. All patients with gastric lymphomas had chemotherapy alone. The mortality rate was 22% predominantly in younger patients with aggressive histology subtypes and advanced disease.
KW - Extranodal lymphoma
KW - Non-Hodgkin's lymphoma
KW - Primary gastrointestinal lymphoma
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UR - http://www.scopus.com/inward/citedby.url?scp=77958027288&partnerID=8YFLogxK
M3 - Article
C2 - 23756789
AN - SCOPUS:77958027288
VL - 65
SP - 98
EP - 100
JO - Medical Journal of Malaysia
JF - Medical Journal of Malaysia
SN - 0300-5283
IS - 2
ER -