Chronic mucocutaneous candidiasis with deficient CD2 (E receptor) but normal CD3 mononuclear cells

Lokman Mohd. Noh, S. H. Hussein, K. D. Sukumaran, I. Rose, Norlia Abdullah

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A case of chronic mucocutaneous candidiasis in a Malaysian child who subsequently developed disseminated tuberculosis and toxoplasmosis is described. The phenotype of her peripheral blood mononuclear cells showed discordance for her T cell markers. The presence of a subpopulation of CD2-/CD3+ mononuclear cells leading to an immunodeficiency state is consistent with failure of activation of CD2-mediated alternative pathway resulting in immunodeficiency. Such abnormal CD2-/CD3+ subpopulations have been described in lepromatous leprosy and foetal abortuses.

Original languageEnglish
Pages (from-to)89-93
Number of pages5
JournalJournal of Clinical and Laboratory Immunology
Volume35
Issue number2
Publication statusPublished - 1991

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Chronic Mucocutaneous Candidiasis
Lepromatous Leprosy
Toxoplasmosis
Blood Cells
Tuberculosis
T-Lymphocytes
Phenotype

ASJC Scopus subject areas

  • Immunology

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Chronic mucocutaneous candidiasis with deficient CD2 (E receptor) but normal CD3 mononuclear cells. / Mohd. Noh, Lokman; Hussein, S. H.; Sukumaran, K. D.; Rose, I.; Abdullah, Norlia.

In: Journal of Clinical and Laboratory Immunology, Vol. 35, No. 2, 1991, p. 89-93.

Research output: Contribution to journalArticle

Mohd. Noh, Lokman ; Hussein, S. H. ; Sukumaran, K. D. ; Rose, I. ; Abdullah, Norlia. / Chronic mucocutaneous candidiasis with deficient CD2 (E receptor) but normal CD3 mononuclear cells. In: Journal of Clinical and Laboratory Immunology. 1991 ; Vol. 35, No. 2. pp. 89-93.
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