Characterisation of fucoidan extracted from Malaysian Sargassum binderi

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Abstract

Fucoidan is a sulphated polysaccharide that consists mainly of fucose, normally found in brown seaweeds. In this study, fucoidan was extracted from Sargassum binderi (Fsar) from Malaysia and subsequently characterised. The chemical characteristics of Fsar were found to be different than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidans. NMR analysis proposed that the main structure of Fsar is →3)fuc-2-OSO3 -(1 → 3)fuc(1→. The molecular weight (47.87 kDa) and degree of sulphation (0.20) of Fsar were higher than those of Fysk, at 27.98 kDa and 0.15, respectively. However, Fsar's polydispersity index (1.12) and fucose content (34.50%) were lower than those of Fysk, at 1.88 and 43.30%, respectively. Both Fsar and Fysk showed similar thermo-gravimetric properties with four mass losses, amorphous in nature and negative optical rotations. Results show that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.

Original languageEnglish
Pages (from-to)267-273
Number of pages7
JournalFood Chemistry
Volume209
DOIs
Publication statusPublished - 15 Oct 2016

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Sargassum
fucoidan
Fucose
fucose
Optical rotation
Seaweed
glycosidic linkages
Optical Rotation
Polydispersity
Phaeophyceae
food grades
Malaysia
Sulfates
Polysaccharides
Conformations
Molecular weight
Nuclear magnetic resonance
sulfates
polysaccharides
Molecular Weight

Keywords

  • Characterisation
  • Fucoidan
  • Sargassum binderi
  • Structure analysis

ASJC Scopus subject areas

  • Food Science
  • Analytical Chemistry

Cite this

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title = "Characterisation of fucoidan extracted from Malaysian Sargassum binderi",
abstract = "Fucoidan is a sulphated polysaccharide that consists mainly of fucose, normally found in brown seaweeds. In this study, fucoidan was extracted from Sargassum binderi (Fsar) from Malaysia and subsequently characterised. The chemical characteristics of Fsar were found to be different than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidans. NMR analysis proposed that the main structure of Fsar is →3)fuc-2-OSO3 -(1 → 3)fuc(1→. The molecular weight (47.87 kDa) and degree of sulphation (0.20) of Fsar were higher than those of Fysk, at 27.98 kDa and 0.15, respectively. However, Fsar's polydispersity index (1.12) and fucose content (34.50{\%}) were lower than those of Fysk, at 1.88 and 43.30{\%}, respectively. Both Fsar and Fysk showed similar thermo-gravimetric properties with four mass losses, amorphous in nature and negative optical rotations. Results show that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.",
keywords = "Characterisation, Fucoidan, Sargassum binderi, Structure analysis",
author = "Lim, {Seng Joe} and {Wan Mustapha}, {Wan Aida} and Maskat, {Mohamad Yusof} and Jalifah Latip and Khairiah Badri and Osman Hassan and {Mohd. Yamin}, Bohari",
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AU - Wan Mustapha, Wan Aida

AU - Maskat, Mohamad Yusof

AU - Latip, Jalifah

AU - Badri, Khairiah

AU - Hassan, Osman

AU - Mohd. Yamin, Bohari

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N2 - Fucoidan is a sulphated polysaccharide that consists mainly of fucose, normally found in brown seaweeds. In this study, fucoidan was extracted from Sargassum binderi (Fsar) from Malaysia and subsequently characterised. The chemical characteristics of Fsar were found to be different than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidans. NMR analysis proposed that the main structure of Fsar is →3)fuc-2-OSO3 -(1 → 3)fuc(1→. The molecular weight (47.87 kDa) and degree of sulphation (0.20) of Fsar were higher than those of Fysk, at 27.98 kDa and 0.15, respectively. However, Fsar's polydispersity index (1.12) and fucose content (34.50%) were lower than those of Fysk, at 1.88 and 43.30%, respectively. Both Fsar and Fysk showed similar thermo-gravimetric properties with four mass losses, amorphous in nature and negative optical rotations. Results show that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.

AB - Fucoidan is a sulphated polysaccharide that consists mainly of fucose, normally found in brown seaweeds. In this study, fucoidan was extracted from Sargassum binderi (Fsar) from Malaysia and subsequently characterised. The chemical characteristics of Fsar were found to be different than those of commercial food grade fucoidan (Fysk) and those of previously studied fucoidans. NMR analysis proposed that the main structure of Fsar is →3)fuc-2-OSO3 -(1 → 3)fuc(1→. The molecular weight (47.87 kDa) and degree of sulphation (0.20) of Fsar were higher than those of Fysk, at 27.98 kDa and 0.15, respectively. However, Fsar's polydispersity index (1.12) and fucose content (34.50%) were lower than those of Fysk, at 1.88 and 43.30%, respectively. Both Fsar and Fysk showed similar thermo-gravimetric properties with four mass losses, amorphous in nature and negative optical rotations. Results show that Fsar has fundamental characteristics of fucoidan with different structural conformation i.e. variation in glycosidic linkages and sulphate group orientation.

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