Case series of testicular adrenal rest tumours in boys with congenital adrenal hyperplasia: A single centre experience

S. W. Karen Leong, Loo Ling Wu

Research output: Contribution to journalArticle

Abstract

Testicular adrenal rest tumours (TART) are aberrant adrenal tissue within the testes (1). Although benign, they can lead to obstruction of the seminiferous tubules and infertility in patients with congenital adrenal hyperplasia (CAH). We report six boys who developed TART, a complication of CAH. Diagnosis was confirmed by ultrasound and testicular vein sampling of elevated 17-hydroxyprogesterone (17-OHP) levels. Glucocorticoids dosages were increased 1½-2 folds to suppress size of the aberrant adrenal tissues. Despite reductions in 17-OHP, the lesions remained unchanged. Three patients had testis-sparing surgery to excise the TART and to preserve normal testicular tissues.

Original languageEnglish
Pages (from-to)92-93
Number of pages2
JournalThe Medical journal of Malaysia
Volume74
Issue number1
Publication statusPublished - 1 Feb 2019

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Adrenal Rest Tumor
Congenital Adrenal Hyperplasia
Testicular Neoplasms
Choristoma
Testis
17-alpha-Hydroxyprogesterone
Seminiferous Tubules
Infertility
Glucocorticoids
Veins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Case series of testicular adrenal rest tumours in boys with congenital adrenal hyperplasia : A single centre experience. / Karen Leong, S. W.; Wu, Loo Ling.

In: The Medical journal of Malaysia, Vol. 74, No. 1, 01.02.2019, p. 92-93.

Research output: Contribution to journalArticle

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