Cardiovascular risk and events in 17 low-, middle-, and high-income countries

S. Yusuf, S. Rangarajan, K. Teo, S. Islam, W. Li, L. Liu, J. Bo, Q. Lou, F. Lu, T. Liu, L. Yu, S. Zhang, P. Mony, S. Swaminathan, V. Mohan, R. Gupta, R. Kumar, K. Vijayakumar, S. Lear, S. AnandA. Wielgosz, R. Diaz, A. Avezum, P. Lopez-Jaramillo, F. Lanas, K. Yusoff, Noor Hassim Ismail, R. Iqbal, O. Rahman, A. Rosengren, A. Yusufali, R. Kelishadi, A. Kruger, T. Puoane, A. Szuba, J. Chifamba, A. Oguz, M. McQueen, M. McKee, G. Dagenais

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Abstract

BACKGROUND: More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons are unknown. METHODS: We enrolled 156,424 persons from 628 urban and rural communities in 17 countries (3 high-income, 10 middle-income, and 4 low-income countries) and assessed their cardiovascular risk using the INTERHEART Risk Score, a validated score for quantifying risk-factor burden without the use of laboratory testing (with higher scores indicating greater risk-factor burden). Participants were followed for incident cardiovascular disease and death for a mean of 4.1 years. RESULTS: The mean INTERHEART Risk Score was highest in high-income countries, intermediate in middle-income countries, and lowest in low-income countries (P

Original languageEnglish
Pages (from-to)818-827
Number of pages10
JournalNew England Journal of Medicine
Volume371
Issue number9
DOIs
Publication statusPublished - 28 Aug 2014

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Cardiovascular Diseases
Rural Population

ASJC Scopus subject areas

  • Medicine(all)

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Yusuf, S., Rangarajan, S., Teo, K., Islam, S., Li, W., Liu, L., ... Dagenais, G. (2014). Cardiovascular risk and events in 17 low-, middle-, and high-income countries. New England Journal of Medicine, 371(9), 818-827. https://doi.org/10.1056/NEJMoa1311890

Cardiovascular risk and events in 17 low-, middle-, and high-income countries. / Yusuf, S.; Rangarajan, S.; Teo, K.; Islam, S.; Li, W.; Liu, L.; Bo, J.; Lou, Q.; Lu, F.; Liu, T.; Yu, L.; Zhang, S.; Mony, P.; Swaminathan, S.; Mohan, V.; Gupta, R.; Kumar, R.; Vijayakumar, K.; Lear, S.; Anand, S.; Wielgosz, A.; Diaz, R.; Avezum, A.; Lopez-Jaramillo, P.; Lanas, F.; Yusoff, K.; Ismail, Noor Hassim; Iqbal, R.; Rahman, O.; Rosengren, A.; Yusufali, A.; Kelishadi, R.; Kruger, A.; Puoane, T.; Szuba, A.; Chifamba, J.; Oguz, A.; McQueen, M.; McKee, M.; Dagenais, G.

In: New England Journal of Medicine, Vol. 371, No. 9, 28.08.2014, p. 818-827.

Research output: Contribution to journalArticle

Yusuf, S, Rangarajan, S, Teo, K, Islam, S, Li, W, Liu, L, Bo, J, Lou, Q, Lu, F, Liu, T, Yu, L, Zhang, S, Mony, P, Swaminathan, S, Mohan, V, Gupta, R, Kumar, R, Vijayakumar, K, Lear, S, Anand, S, Wielgosz, A, Diaz, R, Avezum, A, Lopez-Jaramillo, P, Lanas, F, Yusoff, K, Ismail, NH, Iqbal, R, Rahman, O, Rosengren, A, Yusufali, A, Kelishadi, R, Kruger, A, Puoane, T, Szuba, A, Chifamba, J, Oguz, A, McQueen, M, McKee, M & Dagenais, G 2014, 'Cardiovascular risk and events in 17 low-, middle-, and high-income countries', New England Journal of Medicine, vol. 371, no. 9, pp. 818-827. https://doi.org/10.1056/NEJMoa1311890
Yusuf, S. ; Rangarajan, S. ; Teo, K. ; Islam, S. ; Li, W. ; Liu, L. ; Bo, J. ; Lou, Q. ; Lu, F. ; Liu, T. ; Yu, L. ; Zhang, S. ; Mony, P. ; Swaminathan, S. ; Mohan, V. ; Gupta, R. ; Kumar, R. ; Vijayakumar, K. ; Lear, S. ; Anand, S. ; Wielgosz, A. ; Diaz, R. ; Avezum, A. ; Lopez-Jaramillo, P. ; Lanas, F. ; Yusoff, K. ; Ismail, Noor Hassim ; Iqbal, R. ; Rahman, O. ; Rosengren, A. ; Yusufali, A. ; Kelishadi, R. ; Kruger, A. ; Puoane, T. ; Szuba, A. ; Chifamba, J. ; Oguz, A. ; McQueen, M. ; McKee, M. ; Dagenais, G. / Cardiovascular risk and events in 17 low-, middle-, and high-income countries. In: New England Journal of Medicine. 2014 ; Vol. 371, No. 9. pp. 818-827.
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AU - Yusuf, S.

AU - Rangarajan, S.

AU - Teo, K.

AU - Islam, S.

AU - Li, W.

AU - Liu, L.

AU - Bo, J.

AU - Lou, Q.

AU - Lu, F.

AU - Liu, T.

AU - Yu, L.

AU - Zhang, S.

AU - Mony, P.

AU - Swaminathan, S.

AU - Mohan, V.

AU - Gupta, R.

AU - Kumar, R.

AU - Vijayakumar, K.

AU - Lear, S.

AU - Anand, S.

AU - Wielgosz, A.

AU - Diaz, R.

AU - Avezum, A.

AU - Lopez-Jaramillo, P.

AU - Lanas, F.

AU - Yusoff, K.

AU - Ismail, Noor Hassim

AU - Iqbal, R.

AU - Rahman, O.

AU - Rosengren, A.

AU - Yusufali, A.

AU - Kelishadi, R.

AU - Kruger, A.

AU - Puoane, T.

AU - Szuba, A.

AU - Chifamba, J.

AU - Oguz, A.

AU - McQueen, M.

AU - McKee, M.

AU - Dagenais, G.

PY - 2014/8/28

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N2 - BACKGROUND: More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons are unknown. METHODS: We enrolled 156,424 persons from 628 urban and rural communities in 17 countries (3 high-income, 10 middle-income, and 4 low-income countries) and assessed their cardiovascular risk using the INTERHEART Risk Score, a validated score for quantifying risk-factor burden without the use of laboratory testing (with higher scores indicating greater risk-factor burden). Participants were followed for incident cardiovascular disease and death for a mean of 4.1 years. RESULTS: The mean INTERHEART Risk Score was highest in high-income countries, intermediate in middle-income countries, and lowest in low-income countries (P

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