Brine shrimp toxicity of fractionated extracts of Malaysian medicinal plants

Muhammad Mukram Mohamed Mackeen, M. N. Khan, Z. Samadi, N. H. Lajis

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The methanol, dichloromethane, petroleum ether, 90% methanol and 1-butanol fractions of 40 Malaysian medicinal plants belonging to 25 families were tested for brine shrimp lethality. Various parts and fractions of eight (20%) plants, viz. Annona muricata, Cerbera odollam, Calophyllum inophyllum, Entada phaseoloides, Pithecellobium jiringa, Crotolaria retusa, Morinda elliptica and Sellaginella willdenovii showed very strong toxicity (LC50: <100 ppm). The methanol extract of the seed of Calophyllum inophyllum showed exceptionally toxic activity (LC50: 5 ppm).

Original languageEnglish
Pages (from-to)131-134
Number of pages4
JournalNatural Product Sciences
Volume6
Issue number3
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Artemia
Calophyllum
Medicinal Plants
Methanol
Toxicity
Morinda
Annona
Apocynaceae
1-Butanol
Poisons
Methylene Chloride
Fabaceae
Seed
Seeds
brine

Keywords

  • Brine shrimp
  • Fractionated extracts
  • Malaysian medicinal plants

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Brine shrimp toxicity of fractionated extracts of Malaysian medicinal plants. / Mohamed Mackeen, Muhammad Mukram; Khan, M. N.; Samadi, Z.; Lajis, N. H.

In: Natural Product Sciences, Vol. 6, No. 3, 2000, p. 131-134.

Research output: Contribution to journalArticle

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