Brain herniation in a neonate

C. Y. Wong, Azizi Abu Bakar, Shareena Ishak, Rohana Jaafar, N. Y. Boo, M. R. Isa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Brain herniation is generally thought to be unlikely to occur in newborns due to the presence of the patent fontanelles and cranial sutures. A review of the literature published from 1993 to 2008 via MEDLINE search revealed no reports on neonatal brain herniation from intracranial tumour. We report a preterm Malay male infant born via elective Caesarean section for antenatally diagnosed intracerebral tumour, which subsequently developed herniation. Cerebral magnetic resonance imaging showed features that were compatible with a large complex intracranial tumour causing mass effect and gross hydrocephalus. Tumour excision was scheduled when the infant was two weeks old. Unfortunately, on the morning of the surgery, he developed signs of brain herniation and had profuse tumour haemorrhage during the attempted excision. Histopathological examination revealed an embryonal tumour, possibly an atypical rhabdoid /teratoid tumour. This case illustrates that intracranial tumours in newborns can herniate and should therefore be closely monitored.

Original languageEnglish
JournalSingapore Medical Journal
Volume51
Issue number10
Publication statusPublished - Oct 2010

Fingerprint

Newborn Infant
Brain
Neoplasms
Cranial Sutures
Rhabdoid Tumor
Hydrocephalus
MEDLINE
Cesarean Section
Magnetic Resonance Imaging
Hemorrhage

Keywords

  • Brain herniation
  • Intracranial brain tumours
  • Neonate

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Brain herniation in a neonate. / Wong, C. Y.; Abu Bakar, Azizi; Ishak, Shareena; Jaafar, Rohana; Boo, N. Y.; Isa, M. R.

In: Singapore Medical Journal, Vol. 51, No. 10, 10.2010.

Research output: Contribution to journalArticle

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