Blindness in a pulseless young woman

Lessons learned

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To report a young woman who presented with blindness secondary to ocular ischemic syndrome (OIS) as the initial presenting feature of Takayasu arteritis (TA). Design: Case report. Methods: Computer tomography (CT) aortogram showed severely stenosed aortic branches. Fundus fluorescein angiography showed diffuse capillary nonperfusion. Results: With conventional medical therapy of initial pulse of intravenous methylprednisolone followed by oral steroids and methotrexate, her headache, fatigued feeling, and inflammatory markers improved. However, the visual recovery remained poor. Conclusions: OIS in TA may present subacutely and the visual outcome can be poor despite aggressive immunosuppressive therapy.

Original languageEnglish
Pages (from-to)309-311
Number of pages3
JournalOcular Immunology and Inflammation
Volume20
Issue number4
DOIs
Publication statusPublished - Aug 2012

Fingerprint

Takayasu Arteritis
Blindness
Fluorescein Angiography
Methylprednisolone
Immunosuppressive Agents
Methotrexate
Headache
Pulse
Emotions
Steroids
Tomography
Therapeutics

Keywords

  • Ocular ischemic syndrome
  • Takayasu arteritis

ASJC Scopus subject areas

  • Ophthalmology
  • Immunology and Allergy

Cite this

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title = "Blindness in a pulseless young woman: Lessons learned",
abstract = "Purpose: To report a young woman who presented with blindness secondary to ocular ischemic syndrome (OIS) as the initial presenting feature of Takayasu arteritis (TA). Design: Case report. Methods: Computer tomography (CT) aortogram showed severely stenosed aortic branches. Fundus fluorescein angiography showed diffuse capillary nonperfusion. Results: With conventional medical therapy of initial pulse of intravenous methylprednisolone followed by oral steroids and methotrexate, her headache, fatigued feeling, and inflammatory markers improved. However, the visual recovery remained poor. Conclusions: OIS in TA may present subacutely and the visual outcome can be poor despite aggressive immunosuppressive therapy.",
keywords = "Ocular ischemic syndrome, Takayasu arteritis",
author = "Sakthiswary Rajalingham and Osman, {Syazarina Sharis} and Shaharir, {Syahrul Sazliyana} and {Mohamed Said}, {Mohd Shahrir} and Faridah Hanom",
year = "2012",
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language = "English",
volume = "20",
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journal = "Ocular Immunology and Inflammation",
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T1 - Blindness in a pulseless young woman

T2 - Lessons learned

AU - Rajalingham, Sakthiswary

AU - Osman, Syazarina Sharis

AU - Shaharir, Syahrul Sazliyana

AU - Mohamed Said, Mohd Shahrir

AU - Hanom, Faridah

PY - 2012/8

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N2 - Purpose: To report a young woman who presented with blindness secondary to ocular ischemic syndrome (OIS) as the initial presenting feature of Takayasu arteritis (TA). Design: Case report. Methods: Computer tomography (CT) aortogram showed severely stenosed aortic branches. Fundus fluorescein angiography showed diffuse capillary nonperfusion. Results: With conventional medical therapy of initial pulse of intravenous methylprednisolone followed by oral steroids and methotrexate, her headache, fatigued feeling, and inflammatory markers improved. However, the visual recovery remained poor. Conclusions: OIS in TA may present subacutely and the visual outcome can be poor despite aggressive immunosuppressive therapy.

AB - Purpose: To report a young woman who presented with blindness secondary to ocular ischemic syndrome (OIS) as the initial presenting feature of Takayasu arteritis (TA). Design: Case report. Methods: Computer tomography (CT) aortogram showed severely stenosed aortic branches. Fundus fluorescein angiography showed diffuse capillary nonperfusion. Results: With conventional medical therapy of initial pulse of intravenous methylprednisolone followed by oral steroids and methotrexate, her headache, fatigued feeling, and inflammatory markers improved. However, the visual recovery remained poor. Conclusions: OIS in TA may present subacutely and the visual outcome can be poor despite aggressive immunosuppressive therapy.

KW - Ocular ischemic syndrome

KW - Takayasu arteritis

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