Biological activity on the extract of Derris elliptica

An optimization approach to investigate the effect of processing parameters on mortality of Artemia Salina

Saiful Irwan Zubairi, Mohamad Roji Sarmidi, Ramlan Abdul Aziz

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Bio-pesticide has an increasing importance in both commercial agriculture and small plot subsistence farming. One of the sources of bio-pesticide is "Tuba' plant, also known as Derris elliptica. Rotenone (C23H33O6) is one of the bio-active compounds from the extract of Derris elliptica known to be harmless to plants, but highly toxic to many insects and relatively innocuous to mammals. From the preliminary results (of previous study), the optimization process was employed using central composite design (CCD) to study the effects of two processing parameters on mortality (LC50) of Artemia salina. The processing parameters studied were the types of solvent (acetone and ethanol), solvent-to-solid ratio (10 ml/g and 2 ml/g) and raw material particle size (0.5 mm and 5 mm). The biological activity (LC50) was evaluated for all treatment conditions generated from the Design Expert ®software. Various concentrations of rotenoids resin were prepared and exposed to brine shrimps for 6, 12 and 24 hrs. Next, the mortality of Artemia salina was evaluated using probit analysis. The results showed that rotenoids resin extracted from local plant species of Derris was very active (level of toxicity) whereby all treatments produced LC50less than 1 ppm irrespective of different processing parameters used. For that reason, rotenone and other toxic constituents available in the resin were considered the most important toxic constituents of Derris root and proved to exhibit strong "knock off' effect to the aquatic organisms.

Original languageEnglish
Pages (from-to)918-924
Number of pages7
JournalAdvances in Environmental Biology
Volume8
Issue number10
Publication statusPublished - 2014

Fingerprint

Derris elliptica
Derris
Artemia
Artemia salina
rotenoids
resins
bioactive properties
resin
rotenone
Rotenone
lethal concentration 50
mortality
Mortality
Poisons
extracts
pesticides
pesticide
Agriculture
Pesticides
subsistence farming

Keywords

  • Artemia salina
  • Biological activity
  • Derris elliptica
  • Liquid crude extract
  • Probit analysis
  • Rotenone

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Environmental Science(all)

Cite this

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title = "Biological activity on the extract of Derris elliptica: An optimization approach to investigate the effect of processing parameters on mortality of Artemia Salina",
abstract = "Bio-pesticide has an increasing importance in both commercial agriculture and small plot subsistence farming. One of the sources of bio-pesticide is {"}Tuba' plant, also known as Derris elliptica. Rotenone (C23H33O6) is one of the bio-active compounds from the extract of Derris elliptica known to be harmless to plants, but highly toxic to many insects and relatively innocuous to mammals. From the preliminary results (of previous study), the optimization process was employed using central composite design (CCD) to study the effects of two processing parameters on mortality (LC50) of Artemia salina. The processing parameters studied were the types of solvent (acetone and ethanol), solvent-to-solid ratio (10 ml/g and 2 ml/g) and raw material particle size (0.5 mm and 5 mm). The biological activity (LC50) was evaluated for all treatment conditions generated from the Design Expert {\circledR}software. Various concentrations of rotenoids resin were prepared and exposed to brine shrimps for 6, 12 and 24 hrs. Next, the mortality of Artemia salina was evaluated using probit analysis. The results showed that rotenoids resin extracted from local plant species of Derris was very active (level of toxicity) whereby all treatments produced LC50less than 1 ppm irrespective of different processing parameters used. For that reason, rotenone and other toxic constituents available in the resin were considered the most important toxic constituents of Derris root and proved to exhibit strong {"}knock off' effect to the aquatic organisms.",
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AU - Aziz, Ramlan Abdul

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