Binding study of carbon dots to bovine serum albumin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To increase the efficiency of carbon dots (C-dots), surface of C-dots were functionalized with bovine serum albumin (BSA). The synthesized C-dot were naturally luminescence and it has a high potential to be a biomarker in biomedical field. Bovine serum is a serum protein which were widely using in biosensor area. Therefore binding mechanisms between C-dots and BSA is important to be study. This research reported two binding methods between C-dots and BSA which is formation of covalent bond and adsorption on the surface of BSA. Ultraviolet-Visible and Fourier transformed infrared analysis shows the breaking and formation of amide bond. For the adsorption binding method, the carbonyl bond peak was still appeared after the surface was functionalized with BSA. Both the binding study shows the fluorescence properties with similar intensity. Therefore this research suggesting adsorption binding method is an environmental friendly and more favorable method.

Original languageEnglish
Title of host publication2018 UKM FST Postgraduate Colloquium
Subtitle of host publicationProceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium
EditorsNoor Hayati Ahmad Rasol, Kamarulzaman Ibrahim, Siti Aishah Hasbullah, Mohammad Hafizuddin Hj. Jumali, Nazlina Ibrahim, Marlia Mohd Hanafiah, Mohd Talib Latif
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418431
DOIs
Publication statusPublished - 27 Jun 2019
Event2018 UKM FST Postgraduate Colloquium - Selangor, Malaysia
Duration: 4 Apr 20186 Apr 2018

Publication series

NameAIP Conference Proceedings
Volume2111
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference2018 UKM FST Postgraduate Colloquium
CountryMalaysia
CitySelangor
Period4/4/186/4/18

Fingerprint

bovine serum albumin
albumins
serums
serum
carbon
adsorption
luminescence
biosensors
amides
methodology
blood proteins
biomarkers
covalent bonds
bovine
fluorescence
bioinstrumentation
biomarker
cattle
proteins
protein

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science
  • Physics and Astronomy(all)
  • Nature and Landscape Conservation

Cite this

Mat Lazim, M. A. S., Sonthanasamy, R. S. A., & Tan @ Chong, L. L. (2019). Binding study of carbon dots to bovine serum albumin. In N. H. A. Rasol, K. Ibrahim, S. A. Hasbullah, M. H. H. Jumali, N. Ibrahim, M. M. Hanafiah, & M. T. Latif (Eds.), 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium [050012] (AIP Conference Proceedings; Vol. 2111). American Institute of Physics Inc.. https://doi.org/10.1063/1.5111260

Binding study of carbon dots to bovine serum albumin. / Mat Lazim, Mohamad Azwani Shah; Sonthanasamy, Regina Sisika A.; Tan @ Chong, Ling Ling.

2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. ed. / Noor Hayati Ahmad Rasol; Kamarulzaman Ibrahim; Siti Aishah Hasbullah; Mohammad Hafizuddin Hj. Jumali; Nazlina Ibrahim; Marlia Mohd Hanafiah; Mohd Talib Latif. American Institute of Physics Inc., 2019. 050012 (AIP Conference Proceedings; Vol. 2111).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mat Lazim, MAS, Sonthanasamy, RSA & Tan @ Chong, LL 2019, Binding study of carbon dots to bovine serum albumin. in NHA Rasol, K Ibrahim, SA Hasbullah, MHH Jumali, N Ibrahim, MM Hanafiah & MT Latif (eds), 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium., 050012, AIP Conference Proceedings, vol. 2111, American Institute of Physics Inc., 2018 UKM FST Postgraduate Colloquium, Selangor, Malaysia, 4/4/18. https://doi.org/10.1063/1.5111260
Mat Lazim MAS, Sonthanasamy RSA, Tan @ Chong LL. Binding study of carbon dots to bovine serum albumin. In Rasol NHA, Ibrahim K, Hasbullah SA, Jumali MHH, Ibrahim N, Hanafiah MM, Latif MT, editors, 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. American Institute of Physics Inc. 2019. 050012. (AIP Conference Proceedings). https://doi.org/10.1063/1.5111260
Mat Lazim, Mohamad Azwani Shah ; Sonthanasamy, Regina Sisika A. ; Tan @ Chong, Ling Ling. / Binding study of carbon dots to bovine serum albumin. 2018 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2018 Postgraduate Colloquium. editor / Noor Hayati Ahmad Rasol ; Kamarulzaman Ibrahim ; Siti Aishah Hasbullah ; Mohammad Hafizuddin Hj. Jumali ; Nazlina Ibrahim ; Marlia Mohd Hanafiah ; Mohd Talib Latif. American Institute of Physics Inc., 2019. (AIP Conference Proceedings).
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