Atopic sensitization of children with rhinitis in Malaysia

Balwant Singh Gendeh, S. H. Mujahid, S. Murad, M. Rizal

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Atopy is defined as the genetic propensity to develop immunoglobulin E antibodies in response to exposure to allergens and assessed by skin prick test (SPT) responses to common allergens, which may contribute to the development of the clinical disorders (phenotype). Although it is generally agreed that atopy is an important risk factor for allergic diseases such as asthma, rhinitis, and eczema, the extent to which atopy accounts for these diseases is controversial. One hundred forty one children (up to 12 years) were skin prick tested to evaluate 16 foods common to the Malaysian diet and 4 common aeroallergens. Eighty-five percent of patients had positive SPT reactivity. The most commonly implicated aeroallergen and food allergen was house dust mite (HDM) and Prawn. Seventy percent had positive SPT reactivity results to HDM and 24.8% to prawns. Fifty five percent were positive to more than one allergen and 17.7% positive to single aeroallergen. The prevalence of atopy in children with history of eczema was 90%. The incidence of HDM and food allergy especially crabs and prawns, is significantly greater in Malaysian Children with rhinitis symptoms.

Original languageEnglish
Pages (from-to)522-529
Number of pages8
JournalMedical Journal of Malaysia
Volume59
Issue number4
Publication statusPublished - Oct 2004

Fingerprint

Malaysia
Rhinitis
Skin Tests
Allergens
Pyroglyphidae
Eczema
Dermatophagoides Antigens
Food
Food Hypersensitivity
Immunoglobulin E
Antibody Formation
Asthma
Diet
Phenotype
Skin
Incidence

Keywords

  • Aeroallergens
  • Atopy
  • Children
  • Food allergens
  • Rhinitis
  • Skin prick test

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gendeh, B. S., Mujahid, S. H., Murad, S., & Rizal, M. (2004). Atopic sensitization of children with rhinitis in Malaysia. Medical Journal of Malaysia, 59(4), 522-529.

Atopic sensitization of children with rhinitis in Malaysia. / Gendeh, Balwant Singh; Mujahid, S. H.; Murad, S.; Rizal, M.

In: Medical Journal of Malaysia, Vol. 59, No. 4, 10.2004, p. 522-529.

Research output: Contribution to journalArticle

Gendeh, BS, Mujahid, SH, Murad, S & Rizal, M 2004, 'Atopic sensitization of children with rhinitis in Malaysia', Medical Journal of Malaysia, vol. 59, no. 4, pp. 522-529.
Gendeh, Balwant Singh ; Mujahid, S. H. ; Murad, S. ; Rizal, M. / Atopic sensitization of children with rhinitis in Malaysia. In: Medical Journal of Malaysia. 2004 ; Vol. 59, No. 4. pp. 522-529.
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