Association of human papillomavirus with denture wearing

Rajan Saini, Nurainina B inti Osman, Mazian Ismail, Farini M ohd Sobri, Thean H ock Tang, Jacinta Santhanam

Research output: Contribution to journalArticle

Abstract

AIM:   To determine the prevalence of human papillomavirus in the oral cavity of denture wearers.

METHODS:   Swabs were collected from 72 denture wearers and 72 controls (non-denture wearers) to obtain DNA. Amplification of the β-globin gene was performed by polymerase chain reaction to check the integrity of extracted DNA. The presence of human papillomavirus in the DNA sample was detected by nested polymerase chain reaction.

RESULTS:   The prevalence of human papillomavirus was found to be significantly higher in the oral cavity of denture wearers (38/72, 52.8%) than in the controls (17/72, 23.6%; odds ratio = 3.612, confidence interval = 1.771/7.385, P =  0.05). Low-risk human papillomavirus types were found to be more frequent in both groups.

CONCLUSIONS:   The prevalence of human papillomavirus in the oral cavity of denture wearers was found to be significantly higher compared to controls; however, it was mainly low-risk types.

Original languageEnglish
Pages (from-to)241-247
Number of pages7
JournalJournal of investigative and clinical dentistry
Volume2
Issue number4
DOIs
Publication statusPublished - 1 Nov 2011

Fingerprint

Dentures
Mouth
DNA
Polymerase Chain Reaction
Globins
Gene Amplification
Odds Ratio
Confidence Intervals

Keywords

  • buccal mucosa
  • denture wearer
  • human papillomavirus
  • polymerase chain reaction
  • swab

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Association of human papillomavirus with denture wearing. / Saini, Rajan; Osman, Nurainina B inti; Ismail, Mazian; Sobri, Farini M ohd; Tang, Thean H ock; Santhanam, Jacinta.

In: Journal of investigative and clinical dentistry, Vol. 2, No. 4, 01.11.2011, p. 241-247.

Research output: Contribution to journalArticle

Saini, Rajan ; Osman, Nurainina B inti ; Ismail, Mazian ; Sobri, Farini M ohd ; Tang, Thean H ock ; Santhanam, Jacinta. / Association of human papillomavirus with denture wearing. In: Journal of investigative and clinical dentistry. 2011 ; Vol. 2, No. 4. pp. 241-247.
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