Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women

Study on women with and without breast cancer

Norhayati Mohd Zain, Vengkatha Priya Seriramulu, Kanaga Kumari Chelliah, Norhayati Soin, Shantini Arasaratnam

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

High mammographic breast density is an established risk factor for breast cancer whilst bone mineral density is a marker of estrogen cumulative exposure. This study was conducted to compare bone mineral density in Malaysian premenopausal and postmenopausal women; with and without breast cancer. Besides, it was to determine the relationship between bone mineral density and mammographic breast density in these groups. A cross-sectional study on 50 women above 40 years old who underwent mammogram and Dual Energy X-ray Absorptiometry was conducted at the General Hospital Kuala Lumpur for a year. Respondents were chosen using purposive sampling and women who had commenced cancer treatment were excluded from the study. The mean of selected characteristics were compared between groups using independent-T and Mann-Whitney U for continuous and categorical data respectively whilst Chi-square analysis was used to determine the association of bone mineral density and mammographic breast density. A total of 31 and 19 pre-and postmenopausal women respectively. Women with scattered fibroglandular breasts were the most affected by cancer, although, there was no statistical difference (p=0.298). There was no significant difference in women with contraceptive and/or hormone replacement therapy usage with breast density based on the classification of bone mineral density (p=0.214), cancer (p=0.344) and menstrual status (p=0.298). In conclusion, there was an adverse association between bone mineral density and mammographic breast density in both premenopausal and postmenopausal women; with and without breast cancer.

Original languageEnglish
Title of host publication2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509045686
DOIs
Publication statusPublished - 26 Jan 2017
Event2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016 - Dubai, United Arab Emirates
Duration: 4 Dec 20167 Dec 2016

Other

Other2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016
CountryUnited Arab Emirates
CityDubai
Period4/12/167/12/16

Fingerprint

breast
bones
Minerals
Bone
cancer
minerals
Oncology
Hormones
Contraceptive Agents
Estrogens
estrogens
Sampling
X rays
hormones
markers
therapy
sampling

Keywords

  • bone mineral density
  • breast cancer
  • mammographic breast density
  • risk factor

ASJC Scopus subject areas

  • Bioengineering
  • Artificial Intelligence
  • Instrumentation

Cite this

Zain, N. M., Seriramulu, V. P., Chelliah, K. K., Soin, N., & Arasaratnam, S. (2017). Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. In 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016 [7835595] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIOSMART.2016.7835595

Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women : Study on women with and without breast cancer. / Zain, Norhayati Mohd; Seriramulu, Vengkatha Priya; Chelliah, Kanaga Kumari; Soin, Norhayati; Arasaratnam, Shantini.

2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc., 2017. 7835595.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zain, NM, Seriramulu, VP, Chelliah, KK, Soin, N & Arasaratnam, S 2017, Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. in 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016., 7835595, Institute of Electrical and Electronics Engineers Inc., 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016, Dubai, United Arab Emirates, 4/12/16. https://doi.org/10.1109/BIOSMART.2016.7835595
Zain NM, Seriramulu VP, Chelliah KK, Soin N, Arasaratnam S. Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. In 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc. 2017. 7835595 https://doi.org/10.1109/BIOSMART.2016.7835595
Zain, Norhayati Mohd ; Seriramulu, Vengkatha Priya ; Chelliah, Kanaga Kumari ; Soin, Norhayati ; Arasaratnam, Shantini. / Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women : Study on women with and without breast cancer. 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc., 2017.
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