Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer

Norhayati Mohd Zain, Vengkatha Priya Seriramulu, Kanaga Kumari Chelliah, Norhayati Soin, Shantini Arasaratnam

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

High mammographic breast density is an established risk factor for breast cancer whilst bone mineral density is a marker of estrogen cumulative exposure. This study was conducted to compare bone mineral density in Malaysian premenopausal and postmenopausal women; with and without breast cancer. Besides, it was to determine the relationship between bone mineral density and mammographic breast density in these groups. A cross-sectional study on 50 women above 40 years old who underwent mammogram and Dual Energy X-ray Absorptiometry was conducted at the General Hospital Kuala Lumpur for a year. Respondents were chosen using purposive sampling and women who had commenced cancer treatment were excluded from the study. The mean of selected characteristics were compared between groups using independent-T and Mann-Whitney U for continuous and categorical data respectively whilst Chi-square analysis was used to determine the association of bone mineral density and mammographic breast density. A total of 31 and 19 pre-and postmenopausal women respectively. Women with scattered fibroglandular breasts were the most affected by cancer, although, there was no statistical difference (p=0.298). There was no significant difference in women with contraceptive and/or hormone replacement therapy usage with breast density based on the classification of bone mineral density (p=0.214), cancer (p=0.344) and menstrual status (p=0.298). In conclusion, there was an adverse association between bone mineral density and mammographic breast density in both premenopausal and postmenopausal women; with and without breast cancer.

Original languageEnglish
Title of host publication2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509045686
DOIs
Publication statusPublished - 26 Jan 2017
Event2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016 - Dubai, United Arab Emirates
Duration: 4 Dec 20167 Dec 2016

Other

Other2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016
CountryUnited Arab Emirates
CityDubai
Period4/12/167/12/16

Fingerprint

breast
bones
Minerals
Bone
cancer
minerals
Oncology
Hormones
Contraceptive Agents
Estrogens
estrogens
Sampling
X rays
hormones
markers
therapy
sampling

Keywords

  • bone mineral density
  • breast cancer
  • mammographic breast density
  • risk factor

ASJC Scopus subject areas

  • Bioengineering
  • Artificial Intelligence
  • Instrumentation

Cite this

Zain, N. M., Seriramulu, V. P., Chelliah, K. K., Soin, N., & Arasaratnam, S. (2017). Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. In 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016 [7835595] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIOSMART.2016.7835595

Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women : Study on women with and without breast cancer. / Zain, Norhayati Mohd; Seriramulu, Vengkatha Priya; Chelliah, Kanaga Kumari; Soin, Norhayati; Arasaratnam, Shantini.

2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc., 2017. 7835595.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zain, NM, Seriramulu, VP, Chelliah, KK, Soin, N & Arasaratnam, S 2017, Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. in 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016., 7835595, Institute of Electrical and Electronics Engineers Inc., 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016, Dubai, United Arab Emirates, 4/12/16. https://doi.org/10.1109/BIOSMART.2016.7835595
Zain NM, Seriramulu VP, Chelliah KK, Soin N, Arasaratnam S. Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women: Study on women with and without breast cancer. In 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc. 2017. 7835595 https://doi.org/10.1109/BIOSMART.2016.7835595
Zain, Norhayati Mohd ; Seriramulu, Vengkatha Priya ; Chelliah, Kanaga Kumari ; Soin, Norhayati ; Arasaratnam, Shantini. / Association of bone mineral density and mammographic breast density in premenopausal and postmenopausal Malaysian women : Study on women with and without breast cancer. 2016 International Conference on Bio-Engineering for Smart Technologies, BioSMART 2016. Institute of Electrical and Electronics Engineers Inc., 2017.
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