Association between pulse wave velocity with other vascular markers and inflammation among young adults: An evidence-based review

Norizam Salamt, Amilia Aminuddin, Azizah Ugusman, Aini Farzana Zulkefli

Research output: Contribution to journalArticle

Abstract

Studies evaluating the association between pulse wave velocity (PWV), a gold standard measurement of aortic stiffness and established markers of cardiovascular disease (CVD), with other established vascular markers or inflammation among young adult is still scarce. A systematic review of the literature was conducted to identify relevant studies on the association between PWV with other vascular markers or inflammation. Relevant articles from Ovid Medline, Science Direct and Scopus databases were explored between 2009 and March 2018. Original articles published in English measuring any correlation between carotid-femoral PWV (PWVcf) with either augmentation index (AIx), carotid intima media thickness (CIMT) or C-reactive protein (CRP) on young adult with age range between 18 and 45 years old were included. The literature search identified 21 potential articles to be reviewed, which meet all the inclusion criteria. Four articles investigated the correlation between PWVcf with CRP, however only two studies gave significant but weak correlations. As for CIMT, a single relevant article was found and the correlation was not significant. In conclusion, lack of association between PWV and other vascular markers and inflammation may suggest that these vascular markers have their own property in assessing vascular status. Thus, these markers should be measured independently for comprehensive assessment of future CVD risk.

Original languageEnglish
Pages (from-to)2455-2461
Number of pages7
JournalSains Malaysiana
Volume47
Issue number10
DOIs
Publication statusPublished - 1 Oct 2018

Fingerprint

Pulse Wave Analysis
Blood Vessels
Young Adult
Inflammation
Carotid Intima-Media Thickness
C-Reactive Protein
Cardiovascular Diseases
Vascular Stiffness
Thigh
Databases

Keywords

  • Carotid-femoral pulse wave velocity
  • Inflammation
  • Vascular stiffness
  • Young adults

ASJC Scopus subject areas

  • General

Cite this

Association between pulse wave velocity with other vascular markers and inflammation among young adults : An evidence-based review. / Salamt, Norizam; Aminuddin, Amilia; Ugusman, Azizah; Zulkefli, Aini Farzana.

In: Sains Malaysiana, Vol. 47, No. 10, 01.10.2018, p. 2455-2461.

Research output: Contribution to journalArticle

@article{98ccddb9d24b4a9a82b0bbad537a3d58,
title = "Association between pulse wave velocity with other vascular markers and inflammation among young adults: An evidence-based review",
abstract = "Studies evaluating the association between pulse wave velocity (PWV), a gold standard measurement of aortic stiffness and established markers of cardiovascular disease (CVD), with other established vascular markers or inflammation among young adult is still scarce. A systematic review of the literature was conducted to identify relevant studies on the association between PWV with other vascular markers or inflammation. Relevant articles from Ovid Medline, Science Direct and Scopus databases were explored between 2009 and March 2018. Original articles published in English measuring any correlation between carotid-femoral PWV (PWVcf) with either augmentation index (AIx), carotid intima media thickness (CIMT) or C-reactive protein (CRP) on young adult with age range between 18 and 45 years old were included. The literature search identified 21 potential articles to be reviewed, which meet all the inclusion criteria. Four articles investigated the correlation between PWVcf with CRP, however only two studies gave significant but weak correlations. As for CIMT, a single relevant article was found and the correlation was not significant. In conclusion, lack of association between PWV and other vascular markers and inflammation may suggest that these vascular markers have their own property in assessing vascular status. Thus, these markers should be measured independently for comprehensive assessment of future CVD risk.",
keywords = "Carotid-femoral pulse wave velocity, Inflammation, Vascular stiffness, Young adults",
author = "Norizam Salamt and Amilia Aminuddin and Azizah Ugusman and Zulkefli, {Aini Farzana}",
year = "2018",
month = "10",
day = "1",
doi = "10.17576/jsm-2018-4710-22",
language = "English",
volume = "47",
pages = "2455--2461",
journal = "Sains Malaysiana",
issn = "0126-6039",
publisher = "Penerbit Universiti Kebangsaan Malaysia",
number = "10",

}

TY - JOUR

T1 - Association between pulse wave velocity with other vascular markers and inflammation among young adults

T2 - An evidence-based review

AU - Salamt, Norizam

AU - Aminuddin, Amilia

AU - Ugusman, Azizah

AU - Zulkefli, Aini Farzana

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Studies evaluating the association between pulse wave velocity (PWV), a gold standard measurement of aortic stiffness and established markers of cardiovascular disease (CVD), with other established vascular markers or inflammation among young adult is still scarce. A systematic review of the literature was conducted to identify relevant studies on the association between PWV with other vascular markers or inflammation. Relevant articles from Ovid Medline, Science Direct and Scopus databases were explored between 2009 and March 2018. Original articles published in English measuring any correlation between carotid-femoral PWV (PWVcf) with either augmentation index (AIx), carotid intima media thickness (CIMT) or C-reactive protein (CRP) on young adult with age range between 18 and 45 years old were included. The literature search identified 21 potential articles to be reviewed, which meet all the inclusion criteria. Four articles investigated the correlation between PWVcf with CRP, however only two studies gave significant but weak correlations. As for CIMT, a single relevant article was found and the correlation was not significant. In conclusion, lack of association between PWV and other vascular markers and inflammation may suggest that these vascular markers have their own property in assessing vascular status. Thus, these markers should be measured independently for comprehensive assessment of future CVD risk.

AB - Studies evaluating the association between pulse wave velocity (PWV), a gold standard measurement of aortic stiffness and established markers of cardiovascular disease (CVD), with other established vascular markers or inflammation among young adult is still scarce. A systematic review of the literature was conducted to identify relevant studies on the association between PWV with other vascular markers or inflammation. Relevant articles from Ovid Medline, Science Direct and Scopus databases were explored between 2009 and March 2018. Original articles published in English measuring any correlation between carotid-femoral PWV (PWVcf) with either augmentation index (AIx), carotid intima media thickness (CIMT) or C-reactive protein (CRP) on young adult with age range between 18 and 45 years old were included. The literature search identified 21 potential articles to be reviewed, which meet all the inclusion criteria. Four articles investigated the correlation between PWVcf with CRP, however only two studies gave significant but weak correlations. As for CIMT, a single relevant article was found and the correlation was not significant. In conclusion, lack of association between PWV and other vascular markers and inflammation may suggest that these vascular markers have their own property in assessing vascular status. Thus, these markers should be measured independently for comprehensive assessment of future CVD risk.

KW - Carotid-femoral pulse wave velocity

KW - Inflammation

KW - Vascular stiffness

KW - Young adults

UR - http://www.scopus.com/inward/record.url?scp=85057480086&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85057480086&partnerID=8YFLogxK

U2 - 10.17576/jsm-2018-4710-22

DO - 10.17576/jsm-2018-4710-22

M3 - Article

AN - SCOPUS:85057480086

VL - 47

SP - 2455

EP - 2461

JO - Sains Malaysiana

JF - Sains Malaysiana

SN - 0126-6039

IS - 10

ER -