Association between hypertension and periodontitis

Possible mechanisms

Xin Fang Leong, Chun Yi Ng, Badiah Baharin, Srijit Das

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

This review is to examine the current literatures on the relationship between periodontitis and hypertension as well as to explore the possible biological pathways underlying the linkage between these health conditions. Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. Inflammation has received much attention recently and may contribute to a pivotal role in hypertension. Periodontitis, a chronic low-grade inflammation of gingival tissue, has been linked to endothelial dysfunction, with blood pressure elevation and increased mortality risk in hypertensive patients. Inflammatory biomarkers are increased in hypertensive patients with periodontitis. Over the years, various researches have been performed to evaluate the involvement of periodontitis in the initiation and progression of hypertension. Many cross-sectional studies documented an association between hypertension and periodontitis. However, more well-designed prospective population trials need to be carried out to ascertain the role of periodontitis in hypertension.

Original languageEnglish
Article number768237
JournalThe Scientific World Journal
Volume2014
DOIs
Publication statusPublished - 2014

Fingerprint

hypertension
Periodontitis
Hypertension
Oxidative stress
Blood pressure
Biomarkers
Health
Association reactions
Tissue
Inflammation
Chronic Periodontitis
mortality risk
cardiovascular disease
risk factor
biomarker
Oxidative Stress
Cardiovascular Diseases
Cross-Sectional Studies
blood
Blood Pressure

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Medicine(all)

Cite this

Association between hypertension and periodontitis : Possible mechanisms. / Leong, Xin Fang; Ng, Chun Yi; Baharin, Badiah; Das, Srijit.

In: The Scientific World Journal, Vol. 2014, 768237, 2014.

Research output: Contribution to journalArticle

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