Associated factors of coronary heart disease in patients with type 2 diabetes mellitus

Wan Ibrahim Wnorlida, Bachok Norsa'adah, Abd Aziz Aniza, Ghani Norakmar, Syed Mohamed Al-Junid Syed Junid

Research output: Contribution to journalArticle

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Abstract

Objective: Type 2 diabetes mellitus (T2DM) has become a major health problem worldwide. World Health Organization estimated that the number of diabetes in Malaysia will increase by 164% in year 2030 compared to year 2000. T2DM leads to a wide range of known complications, including coronary heart disease (CHD), which is among the top three causes of death in Malaysia. The aim of this study was to identify the associated factors of developing CHD in T2DM patients in Malaysia. Design: Retrospective cohort study. Materials and Methods: A retrospective medical record review of 249 T2DM patients attending diabetic clinics in primary health care in a north-eastern state in Malaysia was carried out between June and November 2010. The main outcome variables were newly developed CHD and time from T2DM diagnosis to the diagnosis of CHD. Data were analyzed using Multivariable Cox proportional hazards regression. Results: The mean (SD) age and length of T2DM were 57.0 (8.82) years and 5.76 (4.06) years, respectively. The majority of patients had T2DM for 10 years and less. Only 14.1% of the patients took insulin. The proportion of hypertension and dyslipidemia were 23% and 46%, respectively. The majority were affected by retinopathy (79.1%), followed by nephropathy (31.9%), neuropathy (8.0%) and stroke (4%). Only 12% developed CHD after the median follow up time of six years. The significant factor association with CHD development among T2DM was history of stroke [Adjusted Hazard Ratio: 3.72 (95% confidence interval: 1.41, 9.77), P = 0.008].

Original languageEnglish
Pages (from-to)668-671
Number of pages4
JournalInternational Medical Journal
Volume20
Issue number6
Publication statusPublished - 2013
Externally publishedYes

Fingerprint

Type 2 Diabetes Mellitus
Coronary Disease
Malaysia
Stroke
Dyslipidemias
Medical Records
Cause of Death
Primary Health Care
Cohort Studies
Retrospective Studies
Confidence Intervals
Insulin
Hypertension

Keywords

  • Diabetes mellitus
  • Heart disease
  • Hypertension
  • Risk factors
  • Stroke

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Associated factors of coronary heart disease in patients with type 2 diabetes mellitus. / Wnorlida, Wan Ibrahim; Norsa'adah, Bachok; Aniza, Abd Aziz; Norakmar, Ghani; Syed Junid, Syed Mohamed Al-Junid.

In: International Medical Journal, Vol. 20, No. 6, 2013, p. 668-671.

Research output: Contribution to journalArticle

Wnorlida, WI, Norsa'adah, B, Aniza, AA, Norakmar, G & Syed Junid, SMA-J 2013, 'Associated factors of coronary heart disease in patients with type 2 diabetes mellitus', International Medical Journal, vol. 20, no. 6, pp. 668-671.
Wnorlida, Wan Ibrahim ; Norsa'adah, Bachok ; Aniza, Abd Aziz ; Norakmar, Ghani ; Syed Junid, Syed Mohamed Al-Junid. / Associated factors of coronary heart disease in patients with type 2 diabetes mellitus. In: International Medical Journal. 2013 ; Vol. 20, No. 6. pp. 668-671.
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