Assessing a photocured self-plasticised acrylic membrane recipe for Na+ and K+ ion selective electrodes

Yook Heng Lee, Elizabeth A H Hall

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

A technique for the fabrication of solid-state ion sensors based on self-plasticising poly(n-butyl acrylate) matrix by photocuring is described. The poly(n-butyl acrylate) membrane was prepared by photocuring a mixture of the monomer n-butyl acrylate, cross-linker, 2-hexanedioldiacrylate and photoinitiator, 2,2-dimethoxy-2-phenylacetophenone under UV irradiation. The optimum composition of the membranes is discussed. The photocured films produced were elastic, tough and exhibited excellent adhesion on Ag/AgCl substrates. In the optimum recipe no inherent anionic site response was observed for the blank membrane, but AIBN produced anionic site impurities if used as initiator. By incorporating ionophores and lipophilic anions during photopolymerisation, ion-selective membranes could be formed in situ on Ag/AgCl substrates. Immobilisation of ionophore was also possible if a photopolymerisable ionophore such as 4-acryloylamidobenzo-15-crown-5 was included during the photocuring process. Solid-state potassium ion sensors (based on valinomycin or immobilised 4-acryloylamidobenzo-15-crown-5) and sodium ion sensor (based on bis[(12-crown-4)methyl]dodecylmethylmalonate) were fabricated using this technique. The potentiometric responses of all these solid-state ion sensors were comparable to the corresponding conventional plasticised poly(vinyl chloride) (PVC)-based ion-selective electrodes. The influence of the composition on the lower detection limit was discussed and preliminary studies of these sensors with artificial serum electrolytes indicated that the coextration of counter and interfering ions (rather than analyte buffering effects) predominated, raising the lower detection limit. Long term exposure in a complex media, e.g. real human blood serum resulted in a potential shift indicative of ion transport with full recovery of the sensor after 12h. The overall manual fabrication reproducibility of the technique was satisfactory with sensors produced from the same batch demonstrated <5% variation in potentiometric performance.

Original languageEnglish
Pages (from-to)25-40
Number of pages16
JournalAnalytica Chimica Acta
Volume443
Issue number1
DOIs
Publication statusPublished - 12 Sep 2001
Externally publishedYes

Fingerprint

Ion-Selective Electrodes
Ion selective electrodes
Acrylics
electrode
Ions
membrane
Membranes
sensor
ion
Ionophores
Sensors
Limit of Detection
Vinyl Chloride
Valinomycin
Ion selective membranes
serum
Ion Transport
Fabrication
Serum
Photopolymerization

Keywords

  • Blood serum electrolyte
  • Cross-linked poly(n-butyl acrylate)
  • Ion-selective membrane
  • Photocure
  • Plasticiser
  • Solid-state ion sensor

ASJC Scopus subject areas

  • Biochemistry
  • Analytical Chemistry
  • Spectroscopy
  • Environmental Chemistry

Cite this

Assessing a photocured self-plasticised acrylic membrane recipe for Na+ and K+ ion selective electrodes. / Lee, Yook Heng; Hall, Elizabeth A H.

In: Analytica Chimica Acta, Vol. 443, No. 1, 12.09.2001, p. 25-40.

Research output: Contribution to journalArticle

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N2 - A technique for the fabrication of solid-state ion sensors based on self-plasticising poly(n-butyl acrylate) matrix by photocuring is described. The poly(n-butyl acrylate) membrane was prepared by photocuring a mixture of the monomer n-butyl acrylate, cross-linker, 2-hexanedioldiacrylate and photoinitiator, 2,2-dimethoxy-2-phenylacetophenone under UV irradiation. The optimum composition of the membranes is discussed. The photocured films produced were elastic, tough and exhibited excellent adhesion on Ag/AgCl substrates. In the optimum recipe no inherent anionic site response was observed for the blank membrane, but AIBN produced anionic site impurities if used as initiator. By incorporating ionophores and lipophilic anions during photopolymerisation, ion-selective membranes could be formed in situ on Ag/AgCl substrates. Immobilisation of ionophore was also possible if a photopolymerisable ionophore such as 4-acryloylamidobenzo-15-crown-5 was included during the photocuring process. Solid-state potassium ion sensors (based on valinomycin or immobilised 4-acryloylamidobenzo-15-crown-5) and sodium ion sensor (based on bis[(12-crown-4)methyl]dodecylmethylmalonate) were fabricated using this technique. The potentiometric responses of all these solid-state ion sensors were comparable to the corresponding conventional plasticised poly(vinyl chloride) (PVC)-based ion-selective electrodes. The influence of the composition on the lower detection limit was discussed and preliminary studies of these sensors with artificial serum electrolytes indicated that the coextration of counter and interfering ions (rather than analyte buffering effects) predominated, raising the lower detection limit. Long term exposure in a complex media, e.g. real human blood serum resulted in a potential shift indicative of ion transport with full recovery of the sensor after 12h. The overall manual fabrication reproducibility of the technique was satisfactory with sensors produced from the same batch demonstrated <5% variation in potentiometric performance.

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