Approaches in methodology for population-based longitudinal study on neuroprotective model for healthy longevity (TUA) among Malaysian Older Adults

Suzana Shahar, Azahadi Omar, Divya Vanoh, Tengku Aizan Hamid, Siti Zamratol Mai Sarah Mukari, Normah Che Din, Nor Fadilah Rajab, Zainora Mohammed, Rahimah Ibrahim, Won Hui Loo, Asheila Meramat, Mohd Zul Amin Kamaruddin, Mohamad Fazdillah Bagat, Rosdinom Razali

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

A number of longitudinal studies on aging have been designed to determine the predictors of healthy longevity, including the neuroprotective factors, however, relatively few studies included a wide range of factors and highlighted the challenges faced during data collection. Thus, the longitudinal study on neuroprotective model for healthy longevity (LRGS TUA) has been designed to prospectively investigate the magnitude of cognitive decline and its risk factors through a comprehensive multidimensional assessment comprising of biophysical health, auditory and visual function, nutrition and dietary pattern and psychosocial aspects. At baseline, subjects were interviewed for their status on sociodemographic, health, neuropsychological test, psychosocial and dietary intake. Subjects were also measured for anthropometric and physical function and fitness. Biospecimens including blood, buccal swap, hair and toenail were collected, processed and stored. A subsample was assessed for sensory function, i.e., vision and auditory. During follow-up, at 18 and 36 months, most of the measurements, along with morbidity and mortality outcomes will be collected. The description of mild cognitive impairment, successful aging and usual aging process is presented here. A total 2322 respondents were recruited in the data analysis at baseline. Most of the respondents were categorized as experiencing usual aging (73 %), followed by successful aging (11 %) and mild cognitive impairment (16 %). The LRGS TUA study is the most comprehensive longitudinal study on aging in Malaysia, and will contribute to the understanding of the aging process and factors associated with healthy aging and mental well-being of a multiethnic population in Malaysia.

Original languageEnglish
Pages (from-to)1-16
Number of pages16
JournalAging clinical and experimental research
DOIs
Publication statusAccepted/In press - 15 Dec 2015

Fingerprint

Longitudinal Studies
Malaysia
Population
Physical Fitness
Cheek
Neuropsychological Tests
Health
Nails
Hair
Morbidity
Mortality
Cognitive Dysfunction
Surveys and Questionnaires

Keywords

  • Longitudinal
  • Mild cognitive impairment
  • Morbidity
  • Mortality
  • Successful aging
  • Usual aging

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Approaches in methodology for population-based longitudinal study on neuroprotective model for healthy longevity (TUA) among Malaysian Older Adults. / Shahar, Suzana; Omar, Azahadi; Vanoh, Divya; Hamid, Tengku Aizan; Mukari, Siti Zamratol Mai Sarah; Che Din, Normah; Rajab, Nor Fadilah; Mohammed, Zainora; Ibrahim, Rahimah; Loo, Won Hui; Meramat, Asheila; Kamaruddin, Mohd Zul Amin; Bagat, Mohamad Fazdillah; Razali, Rosdinom.

In: Aging clinical and experimental research, 15.12.2015, p. 1-16.

Research output: Contribution to journalArticle

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